NCT02423499Unknown不适用
Features Emotional Responses in Adults With Autism: Comparison With Bipolar Disorder
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Physiological emotional response during emotion elicitation in a laboratory session (Pupil size measured by eye tracking, heart rate, electrodermal response, breath rate) during emotion elicitation in a laboratory session
研究概览
简要总结
The objective of this study is to identify the specific characteristics of Autism Spectrum Disorder (ASD) in emotional response profiles and shared with Bipolar Disorder (BD) characteristics.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •For all participants:
- •Age between 18 and 50 years
- •Normal vision (or corrected)
- •Absence of neurological disorder (epilepsy , head trauma, ... )
- •Ability to understand information about the protocol
- •Informed and signed consent
- •normal mood (euthymia)
- •normal or high intelligence
- •Subjects with ASD:
- •Subjects with an autism spectrum disorder according to the DSM-5
- •The diagnosis is confirmed by diagnostic interviews: ADI- R (Autism Diagnostic Interview-Revised) and / or ADOS (Autism Diagnostic Observation Schedule ) .
- •Subjects with bipolar disorder:
- •Diagnosis of bipolar disorder according to DSM-IV-TR or DSM -5
- •The diagnosis is confirmed by the MINI 6.0 (The Mini-International Neuropsychiatric Interview) .
- •Healthy volunteers:
- •Inclusion after checking the national register of healthy volunteers
- •No history of disease of the central nervous system or psychiatric disorder
- •No family history of ASD or BD in the first degree
- •Lack of psychotropic medication or current cardiotropic
- •Lack of psychiatric disorder on Axis I MINI 6.0
- •AQ Score < 32
排除标准
- 未提供
结局指标
主要结局
Physiological emotional response during emotion elicitation in a laboratory session (Pupil size measured by eye tracking, heart rate, electrodermal response, breath rate) during emotion elicitation in a laboratory session
时间窗: average 1 hour
次要结局
- Subjective emotional response during emotion elicitation in a laboratory session(average 1 hour)
- Facial emotional response during emotion elicitation in a laboratory session(average 1 hour)
- Experience sampling method in real life during a week (emotions, activities, social context, burden)(within the first 7 days after inclusion)
- Physiological emotional response in real life (heart rate, electrodermal response, breath rate, actimetry)(within the first 24h approx. after inclusion)
研究者
研究点 (1)
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