Patterns Of Left Ventricular Remodeling In Patients With Aortic Stenosis Assessed By Two-Dimensional And Three-Dimensional Echocardiography
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- Lahey Clinic
- 试验地点
- 1
- 主要终点
- Evaluate 2-dimensional and 3-dimensional echocardiography for LV patterns of remodeling and hypertrophy
研究概览
简要总结
This preliminary study will compare the effectiveness of two-dimensional and three-dimensional echocardiographic measurements of wall thickness and left ventricular mass in patients with Aortic Stenosis
详细描述
This study will evaluate left ventricular patterns of remodeling and hypertrophy in patients with aortic stenosis, and compare two-dimensional echocardiography measurements (wall thickness) with three-dimensional echocardiography data(left ventricular mass). Along with a second objective to assess Doppler diastolic filling indices associated with the various patterns of left ventricular remodeling.
Previous studies(see reference list) were primarily derived from two-dimensional echo data set(based on wall thickness). Various patterns of left ventricular remodeling have been described in response to increased pressure overload.
Three-dimensional echocardiography is a relatively new technique that is being increasingly used in the Echocardiography Lab in selected patients. This technique holds promise of being more accurate for volume-related measurements than the standard 2-dimensional echocardiography techniques.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects more than 18 yrs of age through 90 yrs of age
- •Both male and female
- •Patients with moderate or severe isolated Aortic Stenosis
- •Patients who have been referred for both two-dimensional and three- dimensional echocardiographies.
排除标准
- •Poor acoustic windows
- •h/o CAD and wall motion abnormality
结局指标
主要结局
Evaluate 2-dimensional and 3-dimensional echocardiography for LV patterns of remodeling and hypertrophy
时间窗: 1 hour
次要结局
- Assess doppler diastolic filling indices for patterns of LV remodeling(1 hour)