Effects of an Home-base Physical Activity Program for Counteracting Sarcopenia in Elderly: a Randomized-controlled Trial.
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 16
- 试验地点
- 2
- 主要终点
- Lower limb strength
研究概览
简要总结
Sarcopenia is a pathophysiological process associated with aging and some metabolic conditions characterized by progressive muscle tissue loss, which may lead to loss of strangth and performance and increase risk of falls and fractures, physical disability and premature death. Therefore, it is necessary to identify personalized programs of physical activity and supplementation for elderly population in order to improve their physical functions, muscle strengh and body composition.
With the present project we aime to assess the effect of a feasible home-based exercise program coupled with food supplementation to improve muscle strength, muscle volume and muscle physical performance potentially associated with sarcopenia in elderly people.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 60 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Sedentary lifestyle.
- •Cognitively intact.
- •Autonomous walking.
- •Acceptance of informed consent.
排除标准
- •Body mass index lower than 18.5 and uppen than 40 kg/m
- •History of cancer.
- •Pacemaker user.
- •History of epileptic episodes.
- •Endocrine-metabolic, neurological, muscular and ortopedic pathologies that affect movement functions.
- •Bone fractures that influence movement functions.
- •Surgical treatments in the prior 6 months.
- •Use of antieptilectics, glucocorticoids, rhGH and testosterone.
- •Hepatic and muscular pathologies
结局指标
主要结局
Lower limb strength
时间窗: Baseline and Week 24
Assessed by chair stand test
次要结局
- Body composition(Baseline and Week 24)
- Quantify thigh cross sectional area(Baseline and Week 24)
- Maximum isometric force that a hand can squeeze(Baseline and Week 24)
- Maximal Isometric Strength of Knee flexors and extensors(Baseline AND Week 24)
- Dynamic balance and gait deficits(Baseline and Week 24)