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临床试验/NCT05799911
NCT05799911已完成不适用

Effect of Molecular Hydrogen Administration on Performance and Body Response on Repeated Exercise and the Following Recovery in National-level Fin-swimmers: A Randomized, Double-blind, Placebo-controlled Crossover Trial

Palacky University2 个研究点 分布在 1 个国家目标入组 14 人开始时间: 2023年4月11日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
14
试验地点
2
主要终点
Swimming time for 400 m

研究概览

简要总结

The aim of this randomized, double-blind, placebo-controlled crossover trial is to evaluate the effect of hydrogen-rich water consumption on performance, recovery, psychological and biochemical outcomes in elite Czech fin-swimmers.

详细描述

Twelve Czech national and international-level fin-swimmers participate in this trial. Participants take molecular hydrogen via drinking hydrogen-rich water (HRW) or placebo three days before (1260 ml/day) and during testing day (2520 ml). All participants participate in two testing session and receive HRW and placebo in random order. Each session includes two training units in a 25-m indoor swimming pool and a 24-hour monitored recovery. The first training unit takes place in the morning between 9 and 11 AM and includes three high intensity interval sets. The afternoon training unit includes a continuous 400-m competitive performance. The washout period between testing sessions is 7 days. The variables assessed are as follows: swimming times, heart rate variability, lower limb explosive strength, rating of perceived exertion, subjective perceived muscle soreness, creatine kinase, blood lactate, and protein carbonyls. Statistical analysis is based on analysis of variance for repeated measures with factors: water (HRW and placebo), time, and interaction. Fisher's post-hoc tests is used for pairwise comparisons. The significance level is set at 0.05.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
Double (Participant, Investigator)

盲法说明

Visually indistinguishable packages of hydrogen-rich water and placebo.

入排标准

年龄范围
16 Years 至 30 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Junior or adult Czech fin-swimming representative.
  • Medical eligibility for competitive sport.
  • Good health condition.
  • Signed informed consent.

排除标准

  • Acute health problems.
  • Not following instructions (free of any supplements three weeks before experiment, free of any medicaments, no caffeine at least 24 hours before experiment).
  • Menstruation in testing session.

研究组 & 干预措施

Molecular hydrogen

Experimental

Hydrogen-rich water supplied in 420-ml packages. 3 days before testing day - 3 packages per day, testing day - 6 packages, 15 packages in total.

干预措施: Hydrogen rich water (Dietary Supplement)

Placebo

Placebo Comparator

Tap water supplied in 420-ml packages. 3 days before testing day - 3 packages per day, testing day - 6 packages, 15 packages in total.

干预措施: Placebo (Dietary Supplement)

结局指标

主要结局

Swimming time for 400 m

时间窗: Change between values before and after 7 days of crossover.

Swimming time is recorded according to swimming and fin-swimming rules. Swimming time is measured by two qualified timekeepers. The longer time is the official time.

次要结局

  • Swimming time for 50 m(Change between values before and after 7 days of crossover.)
  • Protein carbonyls(Change between values before and after 7 days of crossover.)
  • Subjective perceived muscle soreness(Change between values before and after 7 days of crossover.)
  • Lower limb explosive strength(Change between values before and after 7 days of crossover.)
  • Heart rate variability(Change between values before and after 7 days of crossover.)
  • Rating of perceived exertion(Change between values before and after 7 days of crossover.)
  • Creatine kinase(Change between values before and after 7 days of crossover.)
  • Blood lactate(Change between values before and after 7 days of crossover.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jakub Krejci

Palacky University, Faculty of Physical Culture

Palacky University

研究点 (2)

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