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临床试验/NCT04906161
NCT04906161Unknown不适用

Correlation Between Vitamin D and Serum Calcium Level Insufficiency and Early Dental Implant Failure

Ain Shams University2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2021年1月20日最近更新:
适应症

试验速览

阶段
不适用
入组人数
30
试验地点
2
主要终点
Implant success with normal serum vitamin D level

研究概览

简要总结

In this study there is a trial to investigate whether there is a correlation between early implant failure and low serum levels of vitamin D.

详细描述

Osseointegration is a complex phenomenon and depends on many factors; some are related to the implant (material, macroscopic design, and implant surface), others to the surgical-prosthetic protocol (surgical technique, loading conditions, and time), and others to the patient (quantity/quality of bone at the receiving site and the host response)

All these observations would suggest the existence of specific patient-related risk factors such as vitamin D deficiency in the blood, could play an important role in the occurrence of early dental implant failures (EDIFs), but unfortunately are neglected by the dental literature.

In this study there is a trial to investigate whether there is a correlation between early implant failure and low serum levels of vitamin D. Therefore we are including patients with early implant failure during the year 2020 using the same implant (material, macroscopic design, and implant surface), surgical-prosthetic protocol (surgical technique, loading conditions, and time)

The study will be performed into 15 male and 15 female participants that had dental implant placement in the last 3 months. An informed consent will be signed with the patient with full detail on the study.

The situation of the implant will be categorized into either successful or failed dental implant.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
20 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Missing single tooth
  • Systemically free
  • Average body mass index

排除标准

  • Systemic conditions
  • Bad oral hygiene

结局指标

主要结局

Implant success with normal serum vitamin D level

时间窗: 6 months

Implant stability with no further radiographic bone loss following bone remodeling with successful prosthetic part

Early implant failure with deficient serum vitamin D level

时间窗: 6 months

Mobile extruded implant with radiographic bone loss and peri-implant pathosis

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Doaa Adel Salah Khattab

Principle investigator

Ain Shams University

研究点 (2)

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