NCT00395148已完成不适用
A Novel Mechanism Mediating Anti-atherosclerotic and Metabolic Actions of HDL Cholesterol
Bayside Health2 个研究点 分布在 1 个国家目标入组 13 人开始时间: 2006年3月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 13
- 试验地点
- 2
- 主要终点
- Metabolic parameters
研究概览
简要总结
High levels of good cholesterol (HDL) in our blood decreases our chance of having a heart attack. This relates in part to the role good cholesterol plays in reducing build up of fat in the arteries. However, good cholesterol has many other protective effects. We have recently identified three enzymes (proteins) activated by HDL in cells lining the blood vessels, which may be responsible for some of HDL's protective actions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Aged 18 - 65 years
- •Free of overt coronary disease
- •Body mass index <35 kg.m-2
- •Fasting plasma glucose > 7 mmol/L-1
- •No major illness
排除标准
- •Unable to give informed consent
- •Abnormal LFT, U&E, FBE or creatinine
结局指标
主要结局
Metabolic parameters
次要结局
未报告次要终点
研究者
研究点 (2)
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