Effects of a High-intensity Interval Training (HIIT) Exercise Intervention on Sleep in Women Exposed to Trauma: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 41
- 试验地点
- 2
- 主要终点
- Heart Rate Variability
研究概览
简要总结
This study aims to test whether sleep improvements, following 6 weeks of high-intensity interval training exercise among adult women exposed to a traumatic event, are mediated by improvements in heart rate variability or decreased anxiety and hyperarousal symptoms.
详细描述
A total of 60 women with below-average sleep quality and physical activity levels who also screen positive for PTSD on the Post-traumatic Diagnostic Scale (PDS-5) will be randomized to either six weeks of exercise training or a waitlist control. Twenty minutes of high intensity interval training will be performed three times per week for six-weeks. Heart rate variability will be measured at rest, during, and following a cognitive task. Psychometric measures supported by strong validity evidence will assess self-reported anxiety and PTSD symptoms, and sleep quality.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 39 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •self-reported exposure to a traumatic event
- •persistent (> 1 month) PTSD-related symptoms adequate to screen positive for PTSD or self-reported history of a prior PTSD diagnosed by a health care professional.
- •poor sleep quality (Pittsburgh Sleep Quality Index >5)
- •failure to meet recommended level of aerobic or resistance training during leisure time. Physical activity for U.S. adults (<150-mins of moderate or 75-mins of vigorous physical activity [or a combination] per week and/or < 2 days a week of resistance training targeting the major muscle groups).
- •able to safely perform high-intensity exercise
- •aged 18-39 years
- •non-smoker
- •willing to avoid alcohol and vigorous physical activity 24 hours before visiting the lab
- •willing to avoid caffeine for 12 hours before visiting the lab
排除标准
- •Pregnant, lactating, or plans to become pregnant over the next 2 months.
- •Individuals who started taking medication for anxiety or depression-related symptoms within the last month.
- •Individuals currently taking beta-blockers or other medications/substances (marijuana and other illegal drugs) that impact heart rate.
- •History of reproductive disorders (e.g., premenstrual dysphoric disorder or polycystic ovary syndrome), cardiovascular (e.g., cardiac arrhythmia), or pulmonary disorders (e.g., asthma).
- •Pain intensity of 8 or greater in the thigh or foot in the past month
- •Probable alcohol use disorder
结局指标
主要结局
Heart Rate Variability
时间窗: Change from Baseline to Week 7
High frequency (HF) and low frequency (LF) domains of heart rate variability will be assessed before, during, and following a cognitive task.
The Posttraumatic Diagnostic Scale-5 (PDS-5)
时间窗: Change from Baseline to Week 7
The PDS-5 consists 24-item scale and will assess PTSD symptoms based on the diagnostic criteria for the DMS-5. The full PDS-5 assesses trauma history, symptom onset, and index of trauma. The total score ranges from 0-80.
State Trait Anxiety Inventory (STAI-Y2)
时间窗: Change from Baseline to Week 7
The STAI-Y2 Trait subscale consists of 20-item and will assess anxiety. The total score ranges from 20-80; higher scores indicate greater trait anxiety.
Pittsburg Sleep Quality Index (PSQI)
时间窗: Change from Baseline to week 7
The PSQI consists of 19 items. Scores range from 0-21, higher scores indicate poorer sleep quality. A global score ≥5 indicates poor sleep quality.
次要结局
未报告次要终点
研究者
Patrick O'Connor
Professor
University of Georgia