Comparison of Single-Dose Versus Three-Day Antibiotic Prophylaxis in Lower Urinary Tract Endourological Procedures: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 200
- 试验地点
- 1
研究概览
简要总结
we plan To compare between 3 day postoperative dose of antibiotics vs single dose antibiotic in lower urinary tract surgeries. It is in practice to use 3 - 5 days of antibiotics for most of the urological procedures. Our goal is to find out the real world data and outcomes after using both the regimens. We will be including people undergoing Lower urinary tract surgeries with negative urine cultures within one week prior to surgery. we will use cefuroxime as antibiotic prophylaxis for all these patients as per institutional protocol. we will get done urine culture on day 3, and follow up the patient till 30 days of postoperative period to look for any symptomatic UTI. study duration would be around 18 months. we willl use computer based block randomization.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •Undergoing elective TURP, TURBT, OIU, BNI, or CLT Preoperative sterile urine culture (within 7 days prior to surgery) Willing and able to provide written informed consent.
排除标准
- •Evidence of preoperative UTI or positive urine culture
- •Immunocompromised status (e.g., HIV with CD4 <200, post-transplant, on immunosuppressants)
- •Chronic kidney disease (Stage IV or above)
- •Known allergy to cefuroxime or beta-lactam antibiotics
- •Patients requiring intraoperative or postoperative antibiotic escalation for other complications.
研究者
Srujan S Dharap
AIIMS Bhubaneswar