Comparison of Hemodynamic Effects of Fractionated Dose Versus Bolus Dose of Hyperbaric Bupivacaine (0.5%) in Spinal Anesthesia for Lower Limb Surgery

Liaquat National Hospital & Medical College1 个研究点分布在 1 个国家目标入组 100 人开始时间: 2027年4月1日最近更新: 2026年6月1日

试验速览

阶段: 2 期
状态: 尚未招募
发起方: Liaquat National Hospital & Medical College
入组人数: 100
试验地点: 1

研究概览研究设计入排标准研究者研究点记录与标识符相似试验

研究概览

简要总结

To assess hemodynamic changes with hyperbaric bupivacaine with spinal anesthesia

详细描述

Assesment of hemodynamic changes like heart rate and blood pressure with hyperbaric bupivacaine in spinal anesthesia when given in fractionanted versus bolus dose manner

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Crossover
主要目的: Prevention
盲法: Double (Participant, Investigator)

入排标准

年龄范围: 18 Years 至 60 Years（Adult）
性别: All
接受健康志愿者: 否

入选标准

•ASA I and II
•Adults 18 to 60 years of age of either gender
•height from 160 to 182cm and BMI from 15 to 29.9kg/m2

排除标准

•ASA III and IV
•Refusal of consent
•any known renal, hepatic, cardiac or cerebrovascular disease
•hypersensitivity to local anaesthetics drug
•spinal deformity or any contra indications to spinal anesthesia

研究者

发起方

Liaquat National Hospital & Medical College

申办方类型

Other

责任方

Principal Investigator

主要研究者

Usama Bhurgri

Principal Investigator

Liaquat National Hospital & Medical College

研究点 (1)

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