Effects of Different Nitrate Formulations on Strength and Endurance Performance in Recreationally Trained Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Maximum oxygen consumption (Vo2max)
研究概览
简要总结
this study compares the acute effects of Nitrate and Nitrate plus citrulline supplementation on physical performance in recreationally trained males and females. This is a cross-over within-participant comparison design concluding three arms (i) 600 mg of Nitrate (N), ii) 600 mg Nitrate and Citrulline (NC) and (iii) Placebo (PL).
Conditions N, NC and PL will be tested one week apart, considering a minimum washout period of 72 hours.
Dependent variables:
- Number of completed repetitions to failure in squat using 75% of 1RM.
- Ventilatory thresholds (VT1) and (VT2) and Vo2 max from a progressive to exhaustion running test (PGT)
- Lactate post (within 1 min of having completed the PGT)
- Rating of perceived exertion (RPE) by the Borg 6-to-20-point scale recorded every 2 min and at the end of the PGT.
- Heart rate associated with VT1, VT2, and Vo2max - Heart rate maximum.
- Maximal aerobic speed (MAS): calculated from the average speed of the last 2 minutes of the PGT.
- time limit test at MAS (conducted after 15 min of having completed the PGT)
详细描述
Aim:
To analyse and compare the acute effect of two different nitrate formulations on strength and endurance performance in young recreationally trained individuals. In a cross-over within-participant comparison design the participants will be assigned either to ingest (i) 600 mg of Nitrate (N), ii) 600 mg Nitrate and Citrulline (NC) and (iii) Placebo (PL).
Design: Cross-over randomised controlled within participant design including one group undertaking three different treatment conditions.
- Nitrate (N) providing 600 mg (9.6 mmol) of Nitrate (NO-3).
- Nitrate + Citrulline (NC) providing 600 mg (9.6 mmol) of Nitrate (NO-3) and 6 g of citrulline-malate.
- Placebo (PLA) Participants (15 or higher) Inclusion criteria: (a) males and females 18-40 years of age; (b) physically active participants with experience in resistance training performing squat and endurance running as habitual exercises (c) free from musculoskeletal limitations or injuries, (d) agree not to ingest any other supplement during the study.
Exclusion criteria: (a) a history of various metabolic conditions or diseases; (b) use of a variety of medications, including but not limited to those with androgenic and/or anabolic effects and/or nutritional supplements known to affect training outcomes such as creatine, proteins, etc. within 6 weeks before the beginning of the study, (c) current use of tobacco products.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Nitrated and citrulline
A gel, providing 600mg of nitrate (9.6 mmol) and 6 g of citrulline-malate
干预措施: Nitrate (Dietary Supplement)
Nitrate
A gel providing 600 mg (9.6 mmol) of nitrate.
干预措施: Nitrate (Dietary Supplement)
Placebo
Placebo in gel format providing negligible amount of nitrate
干预措施: Nitrate (Dietary Supplement)
结局指标
主要结局
Maximum oxygen consumption (Vo2max)
时间窗: through study completion up to 3 weeks
The highest level of oxygen determined during a progressive to exhaustion running test on a treadmill (PGT)
Strength
时间窗: Day 4, 2.5 hours after ingesting the supplement
Ten maximum repetitions set in back squat using 75% of the previously determined maximal strength determined by the maximum amount of kg lifter in one sigulare repetitions
次要结局
- lactate(through study completion up to 3 weeks)
- Heart Rate(through study completion up to 3 weeks)
- Ventilatory thresholds (VT1) and (VT2)(15 minutes after completing the strength test)
- Rate of Perceived Exertion(through study completion up to 3 weeks)
研究者
Fernando Naclerio
Professor
University of Greenwich