Investigating the Effects of Negative Calorie Diet Compared With Low-calorie Diet Under Exercise Condition on Weight Loss and Lipid Profile in Overweight/Obese Middle-aged and Older Men
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 37
- 主要终点
- Weight
研究概览
简要总结
The present study aimed to determine the effects of negative-calorie diet supplemented with exercise, on weight loss and lipid profile, and to compare its efficiency with low-calorie diet with exercise among elderly adult men with abnormal weight gain.
详细描述
Background and Aim: Negative-calorie diet is among the popular dieting guides for weight loss; however, there is still little knowledge about this method. The present study aimed to determine the effects of negative-calorie diet supplemented with exercise, on weight loss and lipid profile, and to compare its efficiency with low-calorie diet with exercise among elderly adult men with abnormal weight gain.
Materials and Methods
Participants included sedentary men (age 45-75 years) with overweight or obesity (n=37). They were randomly divided into 2 groups including negative calorie diet with exercise, and low-calorie diet with exercise. Of all 37 participants, 30 persons completed the treatment. The weight assessment parameters including change in weight and body composition, blood sample tests were performed pre- and three month post-intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 75 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Non-smokers and weight-stable (± 2 kg, for more than one year) with no history of regular exercise in at least three months before the study.
排除标准
- •History of CVD and other disorders such as diabetes, depression, eating disorders, chronic medications, kidney disease, cancer, food allergies or intolerances to items used in meals. Subjects with abnormality in thyroid or Electrocardiograph, any history of anti-obesity medication or weight loss drugs or dietary supplementations for weight control.
结局指标
主要结局
Weight
时间窗: Baseline
assessed in kg
Total cholesterol (Total-C)
时间窗: Baseline
assessed in mg/dl
Low-density lipoprotein -cholesterol (LDL-C)
时间窗: Baseline
assessed in mg/dl
Triglycerides (TG)
时间窗: Baseline
assessed in mg/dl
High-density lipoprotein -cholesterol (HDL-C)
时间窗: Baseline
assessed in mg/dl
次要结局
- Total cholesterol (Total-C)(3-month)
- High-density lipoprotein -cholesterol (HDL-C)(3-month)
- Weight(3-month)
- Low-density lipoprotein -cholesterol (LDL-C)(3-month)
研究者
Mohammadreza Rezaeipour, MD, PhD
Asst. Prof. of sports medicine (sports injury and corrective movement)
University of Sistan and Baluchestan