Cognitive Intervention With Go and Chess in Early and Subjective Cognitive Decline
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- General cognition
研究概览
简要总结
The goal of this clinical trial]is to evaluate if learning to play traditional board games could improve cognition in subjects with mild cognitive impairment and subjective cognitive decline. The main questions it aims to answer are:
- Do Go and Chess improve cognition?
- Is a game better than the other? Is the effect of both games on cognition synergistic?
- Do Go and Chess improve quality of life?
- Do Go and Chess improve mood?
- Do Go and Chess improve lifestyle?
Participants will be randomized to one of four groups:
- Group intervention with Go, once a week, for 12 weeks
- Group intervention with Chess, once a week, for 12 weeks
- Group intervention with Go and Chess, twice a week, for 12 weeks
- Control group
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 55 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of mild cognitive impairment or subjective cognitive decline
- •Willingness to participate in the board games classes
- •Living within 20-minute driving distance from the center
- •Signed informed consent
排除标准
- •Prior knowledge of the the game rules (in case the subject knows one of the two, they can be randomized to the other one)
- •Significant linguistic or sensory impairment (according to clinical judgment)
- •Significant behavioral or psychiatric disturbances (according to clinical judgment)
- •Significant medical comorbidities (according to clinical judgment)
研究组 & 干预措施
Go classes
Subjects randomized to a group intervention with Go lessons once a week for 12 weeks
干预措施: Go classes (Other)
Chess classes
Subjects randomized to a group intervention with Chess lessons once a week for 12 weeks
干预措施: Chess classes (Other)
Go & Chess classes
Subjects randomized to a group intervention with Go and Chess lessons twice a week for 12 weeks
干预措施: Go classes (Other)
Go & Chess classes
Subjects randomized to a group intervention with Go and Chess lessons twice a week for 12 weeks
干预措施: Chess classes (Other)
Control
Subjects randomized to no intervention for 12 weeks
结局指标
主要结局
General cognition
时间窗: 12 weeks
Differences in Montreal Cognitive Assessment between groups \[continuous scale, 0-30, higher scores indicate better performances\]
次要结局
- Digit Span Backwards(12 weeks)
- Semantic fluency(12 weeks)
- Quality of life indicator(12 weeks)
- Digit Span Forward(12 weeks)
- Trail Making Test - part B(12 weeks)
- Trail Making Test - part A(12 weeks)
- Depression(12 weeks)
- Lifestyle(12 weeks)