Effects of Exercise Intensity on Thermoregulation in the Heat in Children and Youth
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Core temperature
研究概览
简要总结
Little is known about how children and youth regulate body temperature during exercise in the heat compared with young adults, including whether differences in whole-body heat exchange contribute to their responses. The goal of this clinical trial is to determine how exercise intensity affects thermoregulation in boys and girls aged 9-16 years compared with young adult men and women aged 20-25 years. Participants will complete three study visits in a hot environment of 36°C (degree Celcius (97°F, degree Farenheit)), performing light-, moderate-, and vigorous-intensity exercise corresponding to metabolic heat production of 120, 160, and 200 W/m² (w=watts, m=meter), respectively. During each visit, participants will complete four 15-minute bouts of exercise (i.e., bout 1, 2, 3 and 4 respectively) separated by 15-minute rest periods. Testing will be performed in a whole-body air calorimeter, a specialized chamber that precisely measures heat lost through evaporation and dry heat exchange and the amount of heat stored in the body. These measurements, together with core temperature and heart rate, will allow researchers to determine how increasing exercise intensity affects the body's ability to lose heat and whether these responses differ between children and youth and young adults.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 9 Years 至 25 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Healthy male or female.
- •Aged 9-16 years or 20-25 years.
- •Habitually active, defined as participating in regular physical activity at least 3 times per week for at least 20 minutes per session over the previous 6 months.
- •Able to understand and communicate in English or French.
- •For participants younger than 18 years, written parental or guardian consent and participant assent are required.
排除标准
- •Acute illness at the time of testing (e.g., cold, flu, or infection).
- •History of a chronic medical condition that may affect thermoregulation, cardiovascular function, or exercise capacity (e.g., cardiovascular disease, metabolic disorders, respiratory disease including asthma requiring regular medication, or neurological disorders).
- •Use of medications known to affect thermoregulation, hydration status, or cardiovascular responses.
- •History of heat-related illness (e.g., heat exhaustion or heat stroke).
- •Digestive abnormalities or gastrointestinal conditions that may contraindicate ingestion of a telemetry pill.
- •Any condition that, in the opinion of the investigators, would compromise participant safety or the integrity of the data.
结局指标
主要结局
Core temperature
时间窗: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)
Core temperature indexed by visceral (telemetry pill) temperature
次要结局
- Evaporative heat loss(End of each of the four 15 minutes exercise bouts (average of last 5 minutes))
- Dry heat loss(End of each of the four 15 minutes exercise bouts (average of last 5 minutes))
- Whole-body total heat loss(End of each of the four 15 minutes exercise bouts (average of last 5 minutes))
- Body Heat Storage(Change from start to the end for each of the four 15 minutes exercise bouts)
- Skin Temperature(End of each of the four 15 minutes exercise bouts (average of last 5 minutes))
- Change in skin temperature(Change from start to the end for each of the four 15 minutes exercise bouts)
- Heart rate(End of each of the four 15 minutes exercise bouts (average of last 5 minutes))
- Thermal Sensation Scale(End of each of the four 15 minutes exercise bouts (average of last 5 minutes))
研究者
Glen P. Kenny
Full Professor
University of Ottawa