TCTR20150903001招募中未知
Comparison of Corneal Biomechanical Properties Between Myopia and Emmetropia in Primary Open Angle Glaucoma Patients and Controls Measured by Ultra-high-speed Scheimpflug Camera
Ratchadapisaeksompoch(Grants for Development of New Faculty Staff)0 个研究点目标入组 132 人开始时间: 2015年9月3日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 132
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 40 Years 至 0 N/A (No limit)（—）
- 性别
- All
入选标准
- •Target population are divided into 4 groups
- •1.Myopia with POAG
- •2.Emmetropia with POAG
- •3. Myopia without glaucoma
- •4. Emmetropia without glaucoma
- •Inclusion Criteria for all groups
- •Age > 40 years
- •Inclusion criteria
- •- IOP ≥ 21 mmHg
- •- Open angle on gonioscopic examination
- •- Characteristic signs of optic disc damage (glaucomatous optic neuropathy)
- •- Glaucomatous visual field defects on perimetry
- •Non-glaucoma group
- •Inclusion criteria
- •Patients with no evidence of
- •- Enlargement of optic disc cup: cup-to-disc (C:D) ratio > 0.5
- •- Focal enlargement of cup disc cup
- •- Loss of retinal nerve fiber layer defect
- •- Asymmetrical of cupping between the patients' eyes (difference > 0.2)
- •- IOP elevation ≥ 21 mmHg
- •- No family history of glaucoma
- •Myopia group
- •Inclusion criteria
- •- Patients who has refractive error (spherical equivalence) ≥ -4.00 D
- •- Patients who has axial length ≥ 26 mm.
- •Emmetropia group
- •Inclusion criteria
- •- Patients who has refractive error (spherical equivalence) between -0.50 and +0.50 D
- •- Patients who has axial length < 26 mm.
排除标准
- •Exclusion Criteria for all groups
- •- Patients with history of any other ocular pathology (except for cataract, posterior vitreous detachment, dry eye without keratitis)
- •- Patients with any corneal pathology
- •- Patients with history of corneal surgery e.g. pterygium excision, refractive surgery
- •- Patients with history of cataract surgery e.g. Phacoemulsification, Extracapsular cataract extraction (ECCE), Intracapsular cataract extraction (ICCE)
- •- Pregnancy
- •- Patients with underlying connective tissue disease
- •- Patients who unable to give consent
- •- Patients who unable to perform the test
- •Exclusion criteria
- •Other types of glaucoma included combined mechanism of glaucoma e.g. POAG with uveitis glaucoma
- •Non-glaucoma group
- •Exclusion criteria
- •Patients who have no data or unable to assess optic disc
研究者
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