The effects of six months Persicaria Minor supplementation on cognitive function, mood, fMRI brain activity and biomarkers among older adults with mild cognitive impairment

Biotropics Malaysia Berhad0 个研究点目标入组 36 人开始时间: 2019年8月30日最近更新: 2021年9月20日

试验速览

2020 Results article in https://pubmed.ncbi.nlm.nih.gov/33076878/ (added 07/09/2021)

•1. Malaysian older adults age between 60-75 years at the time of informed consent
•2. BMI between 20-30 kg/m2
•3. MCI based on Peterson criteria

•1. Alcohol and/or substance dependence
•2. Had any type of neurodegenerative diseases (i.e. Parkinson disease, Alzheimer’s disease, dementia)
•3. Had a diagnosis of a depressive disorder, schizophrenia or score > 5 in Geriatric Depression Scale (GDS)
•4. Had any medical conditions might interfere with the subject’s participation in the trial (i.e. serious diabetes, chronic heart disease, cancer and kidney, liver or renal failure
•5. Had Attention Deficit Hyperactivity Disorder (ADHD). These conditions might interfere with the outcome such as cognition function and psychosocial status
•6. Regular consumer of traditional herbs, vitamin and mineral supplementation for the past six months because it will jeopardize the effect of supplement used in the study
•7. Had a metallic implant, such as prostheses, shrapnel or aneurysm clips, or electronic implants, such as cardiac pacemakers
•8. Claustrophobic
•9. On Hormone Replacement Therapy (HRT)

发起方