ACTRN12610000238077已完成2 期
In critically ill patients with severe sepsis how does continuous beta-lactam infusion compared with intermittent beta-lactam dosing effect pharmacodynamics and clinical response to treatment? A pilot randomised controlled trial.
Beta-Lactam Infusion Group0 个研究点目标入组 60 人开始时间: 2010年3月22日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •1) Confirmed or suspected infection with new organ dysfunction
- •2) Commencement within the previous 24 hours or planned commencement of ticarcillin/clavulanate, piperacillin/tazobactam or meropenem
- •3) Expected or actual ICU stay greater than 48 hours
排除标准
- •1) Allergy or potential allergy to study medications
- •2) Receiving palliative or supportive treatment only at the time of screening
- •3) Receiving contrinuous renal replacement therapy
- •4) No central venous catheter access with 3 or more lumens
- •5) Receipt of the study drug of interest for > 24 hours prior to enrolment
- •6) Discharge from the ICU within 48 hours
研究者
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