Flowchart-Assisted Resuscitation. Standard CPR vs. Chest Compressions Only: What Happened to the Quality?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 84
- 主要终点
- total number of CC achieving the correct depth of 50-60mm.
研究概览
简要总结
ABSTRACT
Background:
More than two thirds of sudden cardiac arrests are witnessed by bystanders. Bystander cardiopulmonary resuscitation (CPR) doubles survival from cardiac arrest. Importantly, even in witnessed cardiac arrests only 20% of the bystanders commence basic life support. Common reasons for not commencing include panicking and the perceived inability to perform CPR correctly. A meta-analysis could demonstrate that a simplification of the algorithm (compression-only dispatcher-assisted bystander CPR) led to a 22% increase in survival-to-hospital discharge. A recently published trial of the research group could demonstrate that the presence of a flowchart has a positive effect on the quality of BLS while at the same time increasing the rescuers' confidence. Nonetheless, performing CPR is exhausting. Previous publications have emphasized increasing fatigue with the duration of CPR efforts in both, standard and chest compressions-only CPR. Consequently, we wanted to test the hypothesis that chest compressions (CC) are delivered more correctly regarding the depth when utilizing the standard BLS algorithm with the aid of a flowchart as compared to the CC only algorithm utilizing an adapted CPR flowchart in a manikin resuscitation model.
Methods:
After consent of the Research Ethics Board of Medical University of Vienna and obtaining written informed consent of the participants, 84 medically untrained laypersons will be randomised to perform flow-chart assisted CPR for 300s following standard CPR guidelines or CC only CPR. The primary outcome parameter will be the total number of CC achieving the correct depth of 50-60mm. Secondary outcome parameters will be hands-off time, the total number of CC, and the compression rate. The total number of delivered rescue breaths, tidal volume, and time to deliver these will also be evaluated. Furthermore, the subjective point of exhaustion affecting the CPR quality, the reason for discontinuation of CPR if stopped within the 300sec. period and the exhaustion at the end of the CPR measures will be evaluated.
详细描述
Study Design The investigation will be conducted as a prospective, randomized controlled study performed by the Department of Anaesthesia, General Intensive Care and Pain Management, Medical University of Vienna, Austria, according to the Good Scientific Practise guidelines of the Medical University of Vienna. The data collection will be conducted in cooperation with the Training Centre of St. John Ambulance, Vienna, Austria.
Study Population Eligible are all volunteers of ≥18 years of age of non-medical profession, irrespective of gender. Exclusion criteria are professional medical training (nurses, medical doctors, physiotherapists, ergotherepeuts, emergency medical technician or equivalent), pregnancy (as by verbal response at the time of recruitment), and parallel participation in a clinical trial, or physical impairment or illness prohibiting physical effort.
Withdrawal and replacement of subjects
Subjects must be withdrawn under the following circumstances:
- at their own request
- if the subject violates the conditions laid out in the consent form/information sheet or disregards instructions by the study personnel
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •≥18 years of age
排除标准
- •professional medical training (nurses, medical doctors, physiotherapists, ergotherepeuts, emergency medical technician or equivalent)
- •pregnancy (as by verbal response at the time of recruitment)
- •parallel participation in a clinical trial
- •physical impairment or illness prohibiting physical effort.
结局指标
主要结局
total number of CC achieving the correct depth of 50-60mm.
时间窗: 5min. CPR
次要结局
- hands-off time(5min CPR)
- the total number of CC(5min CPR)
- compression rate(5min CPR)
研究者
Bernhard Roessler
PD Dr.
Medical University of Vienna