NCT02149758已完成4 期
EFFECT OF SELECTIVE COX-2 INHIBITOR (ETORICOXIB) ALONG WITH SCALING AND ROOT PLANING (SRP) ON CLINICAL PARAMETERS AND SALIVARY LEVEL OF SUPEROXIDE DISMUTASE IN CHRONIC GENERALIZED PERIODONTITIS A DOUBLE-BLIND, PLACEBO-CONTROLLED, DOUBLE-MASKED RANDOMIZED CONTROLLED TRIAL (RCT).
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- change from baseline in salivary SOD level
研究概览
简要总结
The hypothesis is that Etoricoxib act as an adjuvant to SRP in alleviating periodontal inflammation by:
- improving clinical periodontal parameters and,
- improving the salivary SOD levels.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Forty patients with chronic generalized periodontitis
排除标准
- •with system illnesses, allergies, pregnancy, history of any drug intake and periodontal treatment in past 6 months.
研究组 & 干预措施
Etoricoxib
Experimental
Etoricoxib 60 mg once daily
干预措施: Etoricoxib (Drug)
matching placebo
Placebo Comparator
matching placebo once daily
干预措施: Etoricoxib (Drug)
结局指标
主要结局
change from baseline in salivary SOD level
时间窗: 3 months
次要结局
未报告次要终点
研究者
Dr. Sumit Sharad Shetgar
BDS (Post graduate student
Tatyasaheb Kore Dental College
研究点 (1)
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