Autologous Bone Marrow-Derived Cells for Cardioprotection During Heart Surgery - Bone Marrow Cells & Cardioprotection

niversity Hospitals of Leicester0 个研究点目标入组 44 人开始时间: 2007年8月13日最近更新: 2020年7月20日

试验速览

暂无简介。

•Triple vessel coronary artery disease with or without significant disease of the left main stem with indication of elective surgical revascularization
•Left ventricular ejection fraction greater than 40%
•Age 20-80 years
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•In addition to not being compliant to the inclusion criteria, the following criteria will be sufficient to exclude patients from entering the study:
•Cardiogenic shock (need for inotropic drugs, intra-aortic balloon pump)
•Previous CABG
•PCI in the previous 3 months
•History of neoplastic disease
•History of bleeding disorder
•Chronic inflammatory disease
•Active infection
•Renal impairment (creatinine >180mmol/l)
•Liver dysfunction (GOT >2xULN or INR >1.5)
•Chronic treatment with oral antibiotic agents

发起方

niversity Hospitals of Leicester