NCT01506648已完成不适用
Assessment of Zinc Absorption From a Phytic Acid Rich Complementary Food, Consumed by Young Children Immediately After the Addition of the Enzyme Phytase. A Randomized Single Blind Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Fractional absorption of zinc
研究概览
简要总结
Assessment of zinc absorption from a phytic acid rich complementary food, consumed by young children immediately after the addition of the enzyme phytase. A randomized single blind study
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 12 Months 至 24 Months（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •12-24 month old
- •Male of female
- •Height and weight between -2.0 SD and +2.0 SD with respect to WHO child growth standards.
- •No mineral and vitamin supplements 2 weeks prior to the study and during the whole duration of the study
排除标准
- •Body temperature ≥ 37.5°C
- •Hemoglobin ≤ 7g/dL
- •Positive RDT test
- •Any metabolic, gastrointestinal or chronic disease (according to the statement of the subject's parent) known chronic diseases at the gastrointestinal tract)
- •Long term mediation (that may affect zinc metabolism) during the whole study to interact with zinc metabolism (such as kidney diseases or
结局指标
主要结局
Fractional absorption of zinc
时间窗: 33 days
Fractional absorption of zinc is estimated by using the double isotope tracer ratio technique by administering 67Zn as oral and 70Zn as intravenous stable isotopes.The urinary enrichment with both isotopes is measured in a spot urine sample by inductively coupled plasma mass spectrometry.
次要结局
未报告次要终点
研究者
Prof. Michael B. Zimmermann
Prof
Swiss Federal Institute of Technology
研究点 (1)
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