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临床试验/NCT04194190
NCT04194190No Longer Available不适用

Single Patient Protocol: A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab

National Institutes of Health Clinical Center (CC)0 个研究点开始时间: 2019年12月11日最近更新:
相关药物

试验速览

阶段
不适用
状态
No Longer Available

研究概览

简要总结

A single patient will be treated with Individual Patient TCR-Transduced PBL

详细描述

Background:

-Please refer to National Cancer Institute Surgery Branch (NCI-SB) protocol 18-C-0049, Amendment F.

Objective:

-Under Individual Patient Expanded Access, to treat a patient with metastatic breast cancer with autologous peripheral blood lymphocytes (PBL) that have been transduced with genes encoding T-cell receptors that recognize mutated neoantigens in the autologous cancer.

Eligibility:

研究设计

研究类型
Expanded Access

入排标准

接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

研究者

申办方类型
Nih
责任方
Sponsor

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