Prehospital Transport During Advanced Respiratory Support: An International Survey and Prospective Feasibility Evaluation of Portable External Power
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 246
- 试验地点
- 20
- 主要终点
- Number and Percentage of Respondents Reporting Predefined Respiratory-Support Transport Practices
研究概览
简要总结
The HERMES Phase I-II study was a two-phase observational investigation designed to characterize contemporary practices and safety-related challenges associated with the transport of patients requiring advanced respiratory support and to assess the operational feasibility of portable external electrical power during ambulance transport.
Phase I consisted of an international electronic cross-sectional survey of healthcare professionals involved in noninvasive ventilation (NIV) management or patient transport. The survey evaluated reported transport indications, ventilator type and positioning, respiratory interfaces, transport-team composition, and perceived patient-, equipment-, and environment-related problems.
Phase II was a prospective descriptive feasibility evaluation involving 25 ambulance transports performed in Albacete and Bilbao, Spain. Patients were transported while receiving high-flow nasal oxygen (HFNO), rescue NIV, or invasive mechanical ventilation. A portable external power supply was used to support continuity of powered respiratory-support equipment during transport. The primary technical feasibility outcome was successful completion of transport while maintaining respiratory support without reported power interruption, clinically relevant equipment alarm, or technical failure.
The two phases were analyzed independently and were intended to characterize respiratory-support transport practices and evaluate technical and operational feasibility rather than establish comparative effectiveness, clinical superiority, or prevention of clinical deterioration.
详细描述
Patients receiving advanced respiratory support may require prehospital, interhospital, or intrahospital transport for diagnostic procedures, therapeutic interventions, transfer to a higher level of care, or continuation of acute management. Noninvasive ventilation and high-flow nasal oxygen are established forms of respiratory support in acute respiratory failure, while invasive mechanical ventilation remains necessary in patients with more severe or refractory respiratory failure. During transport, continuity of respiratory support must be maintained despite changes in environment, personnel, equipment configuration, oxygen availability, and electrical power supply.
Transport of critically ill patients represents a recognized period of increased clinical and technical vulnerability. International recommendations emphasize adequate stabilization before transport, appropriate physiologic monitoring, trained accompanying personnel, communication between clinical teams, verification of equipment function, sufficient oxygen and power reserves, and contingency planning for foreseeable clinical deterioration or device failure. Prospective cohort studies and systematic reviews have demonstrated that transport-associated adverse events may include physiologic deterioration, equipment malfunction, circuit or airway problems, interruptions in therapy, and organizational or communication failures. The reported frequency of such events varies substantially according to patient population, transport setting, event definitions, urgency, and surveillance methodology.
Against this background, the HERMES Phase I-II program was developed as two analytically distinct observational phases.
Phase I was an international electronic cross-sectional survey targeting healthcare professionals involved in NIV management or patient transport. The objective was to characterize reported clinical and organizational practices related to the transport of patients requiring noninvasive respiratory support and to identify perceived areas of vulnerability during transport.
The available survey records were timestamped from February 20 to May 6, 2023. The dataset contained 224 response records. Survey domains included indications for transport, type and positioning of ventilators, use of respiratory interfaces, composition of the transport team, and categories of patient-, equipment-, and environment-related problems.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Phase I - International Healthcare Professional Survey
- •Inclusion Criteria:
- •Healthcare professionals involved in the management of noninvasive ventilation or in the transport of patients requiring respiratory support.
- •Participation in the international electronic survey addressing respiratory-support transport practices.
排除标准
- •Records not representing participation in the respiratory-support transport survey.
- •Records lacking sufficient information for descriptive analysis of the predefined survey domains.
- •Phase II - Portable External Power Feasibility Evaluation
- •Inclusion Criteria:
- •Patients undergoing ambulance transport while receiving advanced respiratory support.
- •Receipt of high-flow nasal oxygen (HFNO), noninvasive ventilation (NIV), or invasive mechanical ventilation during the transport episode.
- •Transport performed at one of the participating clinical units included in the prospective feasibility evaluation.
- •Availability of transport-level data sufficient to evaluate continuity of respiratory support and the occurrence of power interruption, clinically relevant equipment alarm, or technical failure.
- •Exclusion Criteria:
- •Transport episodes not involving advanced respiratory support.
- •Transport episodes for which continuity of respiratory support or the primary technical feasibility outcome could not be determined.
研究组 & 干预措施
Phase II - Portable External Power Feasibility Cohort
Patients undergoing ambulance transport while receiving advanced respiratory support, including high-flow nasal oxygen, rescue noninvasive ventilation, or invasive mechanical ventilation. Portable external electrical power was prospectively evaluated for continuity of powered respiratory-support equipment during transport. Clinical management and respiratory-support decisions were determined according to routine clinical practice.
干预措施: Portable External Power Supply (Device)
Phase I - International Healthcare Professional Survey
Healthcare professionals involved in noninvasive ventilation management or patient transport who participated in the international electronic cross-sectional survey. The survey assessed reported transport indications, ventilator type and positioning, respiratory-interface use, transport-team composition, and perceived patient-, equipment-, and environment-related problems. The survey dataset contained 224 response records corresponding to 221 unique respondents.
结局指标
主要结局
Number and Percentage of Respondents Reporting Predefined Respiratory-Support Transport Practices
时间窗: Baseline
Number and percentage of Phase I survey respondents reporting predefined respiratory-support transport practices, including transport indications, ventilator type and positioning, respiratory-interface use, and transport-team composition.
Number and Percentage of Ambulance Transports Completed With Uninterrupted Respiratory Support
时间窗: From departure from the point of origin to arrival at the intended destination (transport duration: 23-110 minutes)
Number and percentage of Phase II ambulance transport episodes completed with uninterrupted respiratory support and without reported electrical power interruption, clinically relevant equipment alarm, or technical failure. This outcome represented the primary technical feasibility measure of the portable external power evaluation.
次要结局
- Number and Percentage of Respondents Reporting Transport-Related Problems(Baseline)
- Number and Percentage of Respondents Reporting Each Transport-Team Professional Category(Baseline)
- Number and Percentage of Ambulance Transports by Respiratory-Support Modality(From departure from the point of origin to arrival at the intended destination (transport duration: 23-110 minutes))
- Number and Percentage of Patients Requiring Escalation or Modification of Respiratory Support(From departure from the point of origin to arrival at the intended destination (transport duration: 23-110 minutes))
- Number and Percentage of Ambulance Transports With Power Interruption, Clinically Relevant Equipment Alarm, or Technical Failure(From departure from the point of origin to arrival at the intended destination (transport duration: 23-110 minutes))
- Ambulance Transport Duration in Minutes(From departure from the point of origin to arrival at the intended destination (transport duration: 23-110 minutes))
研究者
Berkan Basançelebi
Lecturer
Medipol University
