Feasibility of Remote Early At-risk Diagnosis for Cerebral Palsy in High-risk Infant Follow-up Clinics in The Central Norway Regional Health Authority
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 100
- 试验地点
- 3
- 主要终点
- Predictability of GMA and computer-based assessment for development of CP
研究概览
简要总结
Cerebral Palsy (CP) is the most common motor dysfunction in childhood. Traditionally, diagnosis is set between 12 and 24 months of age. This study will evaluate feasibility of a new screening procedure for early detection of CP in high-risk infants and investigate how such a procedure can be implemented in the Central Norwegian Regional Health Authority (CNRHA).
The most accurate method to detect and predict CP at an early age is the General Movement Assessment (GMA). GMA is based upon expert observations of infant spontaneous movements in a video. In Central-Norway such expertise is today only present at St. Olavs Hospital, Trondheim University Hospital. Video recordings by health personnel and parents will be used in follow-up programs within CNRHA for remote expert based GMA. In addition, machine learning models will be applied for automatic detection of CP.
Early identification of CP will lead to improved function and increased possibility to direct health care resources to the patients who need it most, independent of geographical and expert based constraints.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 0 Months 至 2 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •hospitalized at a Neonatal Intensive Care Unit (NICU) within the Central Norway Regional Health Authority that is referred to follow-up in the Specialist Health Services containing a team of minimum a pediatrician and a physiotherapist.
- •at high-risk for adverse neurological outcomes as considered by the pediatrician on the basis of clinical judgement (example: serious asphyxia, prematurity, stroke, brain hemorrhage)
排除标准
- •Peripheral neuromotor disease e.g. brachial plexus injury
- •iatrogenic restricted movements (e.g. cast for clubfoot)
结局指标
主要结局
Predictability of GMA and computer-based assessment for development of CP
时间窗: 5 years
Correlation of computer software data between standard video set-up and handheld smartphone video.
时间窗: 1 week
Scorable video for remote GMA
时间窗: 1 week
Predictability of GMA and computer-based assessment for development of CP
时间窗: 2 years
次要结局
未报告次要终点