NL-OMON39556已完成3 期
Randomized Controlled Trial Investigating the Efficacy and Safety of Nebulized Heparin versus Placebo in Burn Patients with Inhalation Trauma - The Hepburn*study
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- informed consent
- •- age > 18 years
- •- need for intubation and mechanical ventilation
- •- clinical diagnosis of inhalation trauma confirmed by bronchoscopy
排除标准
- •- > 36 hours after trauma
- •- Receiving invasive ventilation > 24 hours
- •- Expected duration of mechanical ventilation < 24 hours
- •- Chronic obstructive pulmonary disease GOLD stage III and IV
- •- Any history of pulmonary hemorrhage in the past 3 months
- •- Any history of significant bleeding disorder
- •- Known allergy to heparin, including heparin*induced thrombocytopenia
- •- Pregnancy or breast feeding
- •- Unlikely to survive for > 72 hours
- •- Total body surface area (TBSA) > 60%
- •- Witnessed or proven aspiration (i.e., confirmed by bronchoscopy)
研究者
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