Early Exposure to Lead and Adult Antisocial Outcomes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 225
- 试验地点
- 1
- 主要终点
- Lead Exposure and Antisocial Behavior
研究概览
简要总结
Prior research indicates a link between early lead exposure and risk for delinquent behavior. In this study, we follow a large birth cohort from the Cincinnati Lead Study into early adulthood to determine whether this increased risk persists. Outcome measures include official arrest records, diagnoses of Substance Abuse Disorder and Antisocial Personality Disorder, self-report of delinquent behavior, and a psychopathy scale. Predictors include pre-natal and post-natal blood lead levels. Multivariate statistical methods will control for potential confounders/covariates.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •(1) Part of original CLS birth cohort -
排除标准
- •(1) Moved out of geographic area
结局指标
主要结局
Lead Exposure and Antisocial Behavior
时间窗: Prenatal (1-2 trimester) and postnatal on a quarterly and bi-annual basis (until 6.5 years)
次要结局
未报告次要终点
