Odense Fallers and Osteoporosis Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 322
- 试验地点
- 1
- 主要终点
- Bone mineral density using DXA of hip and spine regions (Hologic machine)
研究概览
简要总结
Osteoporosis and falls occur with increasing frequency among the elderly. Osteoporosis and fall increases the risk of fracture. Falls in the elderly are associated with a high morbidity and mortality with potentially life-threatening consequences of falls including fractures. Besides fracture fall may cause long term problems such as disability fear of falling and loss of independence. Today osteoporosis is diagnosed by bone scan of the hip and spine. The investigators want to investigate whether other more accessible and less expensive testing methods can be used to diagnose osteoporosis. Additionally, the investigators will examine the incidence of osteoporosis among the elderly in the municipality of Odense. Finally, the investigators would like to investigate the association between factors that can lead to falls and to investigate the performance of older and whether there are changes in functional ability over time.
详细描述
Study Objectives
- To define the prevalence of osteoporosis in a falls clinic population, and compare it with two aged matched control groups - fallers not attending the falls clinic and non-fallers.
- To evaluate the usefulness of peripheral bone scanning techniques in a falls clinic population.
- To determine the prevalence of vertebral fractures in a falls clinic population and compare it with two aged matched control groups - fallers not attending the falls clinic and non-fallers
- To investigate functioning, disability, health related quality of life and perceived need for rehabilitation in a falls clinic population including variation in a one year period, and compare it with two aged matched control groups - fallers not attending the falls clinic and non-fallers.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Women aged 65 years or over attending the falls clinic
- •*(There will be no upper age limit to recruitment).
- •Those capable of giving Informed consent.
排除标准
- •Patients under the age of 65 years.
- •Patients unwilling to give informed consent.
- •Cognitively impaired people who are not capable of giving consent.
- •Patients who are not mobile enough to be helped onto a DXA scan table with help
结局指标
主要结局
Bone mineral density using DXA of hip and spine regions (Hologic machine)
时间窗: baseline
Bone mineral density of the phalanges using radiographic absorptiometry (Alara Metriscan machine)
时间窗: baseline
Mental health state
时间窗: one year
Meausered by Mini Mental State Examination (MMSE)
Fall incidences
时间窗: one year
Prevalence of vertebral fractures using instant vertebral assessment mode (IVA) of the DXA machine (Hologic machine)
时间窗: baseline
Broad band ultrasound attenuation of the heel using the heel ultrasound machine (Lunar Achilles machine)
时间窗: baseline
Basis mobility
时间窗: One year
Time up and go, Chair stand, Bergs balance scale, Avlunds scale, gait speed and dual-task will be used
Fear of falling
时间窗: One year
The Falls Efficacy scale - international will be used
Muscle strength in upper and lower extremities
时间窗: One year
A dynamometer will be used
Health related quality of life
时间窗: one year
Self Reporting Questionnaire will be used
Perceived need
时间窗: one year
Self Reporting Questionnaire
次要结局
未报告次要终点
研究者
Katja Thomsen
ph.d.student
University of Southern Denmark