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临床试验/NCT07582640
NCT07582640尚未招募不适用

Erector Spinae Plane Block Versus Transversus Abdominis Plane Block For Postoperative Analgesia In Cesarean Section: Comparative Randomized Prospective Study

Sohag University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2026年4月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
60
试验地点
1

研究概览

简要总结

This study is a prospective randomized controlled trial designed to compare the effectiveness of the erector spinae plane (ESP) block versus the transversus abdominis plane (TAP) block for postoperative analgesia in patients undergoing cesarean section under spinal anesthesia. Sixty patients will be randomly allocated into two equal groups to receive either ESP or TAP block after surgery.

The primary outcome of the study is the assessment of postoperative pain using the Numeric Rating Scale (NRS) over the first 24 hours. Secondary outcomes include total morphine consumption, time to first request for rescue analgesia, patient satisfaction, incidence of complications, and hemodynamic stability.

All patients will receive standardized spinal anesthesia followed by the assigned block using a combination of bupivacaine and lidocaine under ultrasound guidance. Postoperatively, a multimodal analgesic regimen will be applied, including regular paracetamol and rescue analgesia with ketorolac or morphine based on pain scores.

The rationale of the study is based on the limitation of the TAP block in providing only somatic analgesia, whereas the ESP block may offer both somatic and visceral pain control due to its wider spread. Therefore, the study aims to determine whether ESP block provides superior postoperative analgesia and reduces opioid requirements compared to TAP block after cesarean delivery.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Age from 18 to 40 years old.
  • Pregnant women.
  • Scheduled for lower-segment cesarean section.
  • American Society of Anesthesiologists (ASA) physical status I-II.
  • Singleton pregnancy at ≥37 weeks' gestation.

排除标准

  • • Contraindications to regional blocks or local anesthetics.
  • History of chronic analgesic use or opioid dependency.
  • Coagulopathy or anticoagulant therapy.
  • Local infection at the injection site.
  • Allergy to study medications.
  • Patient refusal.

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohamed Ali Elyamany

Resident of Anesthesia, Surgical Intensive Care and Pain Management Faculty of Medicine, Sohag University

Sohag University

研究点 (1)

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