NCT03629574Unknown不适用
Evaluation of a Protocol of Protective Mechanical Ventilation During Cardiopulmonary Bypass in Cardiosurgery for Congenital Heart Diseseas
Azienda Ospedaliera di Padova1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2018年8月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Evaluation of the damage of the air-blood membrane in a ventilation protocol and a non ventilation protocol during cardiopulmonary bypass
研究概览
简要总结
The study is about a protocol of protective mechanical ventilation during cardiopulmonary bypass used during cardiosurgery for the correction of congenital heart diseases, to evaluate what's the best for the lungs
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- — 至 5 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •congenital heart diseases
- •younger than 5 years
- •CPB longer than 30 minutes in hypotermia
- •elective surgery
- •stable clinical conditions
排除标准
- •genetic anomalies
- •mechanical ventilation before the surgery
- •kidney injuries
- •hepatic failure
结局指标
主要结局
Evaluation of the damage of the air-blood membrane in a ventilation protocol and a non ventilation protocol during cardiopulmonary bypass
时间窗: Baseline, and 6, 12, 24 and 48 hours after the surgery
It will be assed the plasma level of proteins which usually are absent in the plasma (surfactant protein A and B) that change as a damage of the air-blood membrane appears.
次要结局
未报告次要终点
研究者
Cristiana Carollo
Medical Doctor
Azienda Ospedaliera di Padova
研究点 (1)
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