Study of Pelvic Organ Mobility by Dynamic MRI in Pelvic Endometriosis
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- the mean vertical displacement (in millimeters) measured on the anterior wall of the vagina between rest and maximum pushing force during dynamic MRI
研究概览
简要总结
Endometriosis is a frequent pathology with an estimated prevalence of 10% of women of childbearing age. There is no exact correspondence between the symptoms described by the patients and the severity of the lesions, which makes clinical diagnosis difficult. It therefore seems important to improve the complementary examinations available to make the diagnosis more precise and to better study the effectiveness of the treatments implemented. The clinical examination and per-surgical findings of patients with deep pelvic endometriosis show a clear decrease in the mobility of the pelvic organs in relation to each other, but few studies have looked at this mobility, which could however have an implication in explaining the pathophysiology of the disease and the symptomatology of the patients, as well as in the detection of lesions preoperatively. The persistence of hypo-mobility could also help to understand treatment failures.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patient referred for suspected pelvic endometriosis requiring pelvic MRI
- •Female, nulliparous,
- •patient with signed written consent, patient with health insurance,
- •patient willing to comply with all study procedures and duration
排除标准
- •BMI > 35,
- •history of hereditary collagen and elastic tissue disease,
- •history of pelviperitonitis,
- •history of major pelvic surgery,
- •inability to receive informed information,
- •inability to participate in the entire study,
- •lack of social security coverage,
- •refusal to sign consent
结局指标
主要结局
the mean vertical displacement (in millimeters) measured on the anterior wall of the vagina between rest and maximum pushing force during dynamic MRI
时间窗: Baseline
次要结局
- the statistical association between the symptoms of patients with endometriosis and the mean vertical displacement (in millimetres) on the wall of each pelvic organ at the push effort during dynamic MRI.(Baseline)
- the measurement of variation in mean vertical displacement (in millimetres) on the wall of each pelvic organ at the push effort between the initial dynamic MRI of patients with(Baseline)
- the mean vertical displacement (in millimetres) measured on the cervix between rest and maximum thrust effort during dynamic MRI.(Baseline)
- the mean vertical displacement (in millimetres) measured on the posterior wall of the vagina between rest and maximum pushing force during dynamic MRI.(Baseline)