The Effect of a Combination Between Clinical Crown Lengthening Surgery and Botulinum Toxin A Injection in Gummy Smile Treatment
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Clinical crown length
研究概览
简要总结
Background: The demand for beauty is increasing in society as everyone is looking for cosmetic improvement, including gummy smile correction.
Object: This study aims to evaluate the efficacy of a combination of a clinical tooth crowns lengthening surgery following by a BTX-A injection in gummy smile treatment upon based on clinical assessment and photography
Method: An uncontrolled longitudinal study was implemented at the Faculty of Odonto-Stomatology (FOS) of the University of Medicine and Pharmacy at Ho Chi Minh City (UMPH), Viet Nam, from August 2020 to May 2021. Twenty patients (19 females and one male) at a mean age of 24 years old who came for gummy smile chief complaint were included in the study. Subjects were operated to lengthen the clinical crown following an additional botulinum toxin A injection two months post-surgery. All the participants answered the smile esthetic satisfactory questions and were photographed at the time before treatment (T0), two months after clinical crown lengthening surgery (T1), two weeks (T2), and two months (T3) follow-up visits after BTX-A injection. The gingival exposure (GE) and clinical crown length (CCL) were measured at each time point for analysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Gummy smile because of 2 combined etiologies:
- •Short clinical crown of teeth due to the altered passive tooth eruption
- •Hyperactivity of upper lip muscles (lip mobility level > 8mm)
排除标准
- •Pregnant or breastfeeding patients
- •Gummy smiles due to:
- •Maxillary bone overgrowth (maxillary hypertrophy)
- •Vertical maxillary excess
- •Neuromuscular disorder
- •Gingival hyperplasia due to medicine, supplements, or neuromuscular transmission inhibiting agents
- •Systematic diseases that can affect the result of surgical treatment (such as diabetes, heart disease taking blood anticoagulant medicament, blood diseases, immunodeficiency disease etc.)
- •Allergy to BTX-A or albumin
- •History of taking BTX-A injection in the head-neck area formerly
- •Patient with any contraindication of surgery
结局指标
主要结局
Clinical crown length
时间窗: Two months after Botulinum toxin A injection (T2)
The clinical crown length is measured in millimeters using digital caliper and periodontal probe
Gingival exposure
时间窗: Two months after Botulinum toxin A injection (T2)
The outcome is measured in millimeters based on photos of subjects included
次要结局
未报告次要终点
研究者
Nguyen Thu Thuy
Deputy Head of Department of Periodontology
University of Medicine and Pharmacy at Ho Chi Minh City