NCT02194972已完成3 期
Study of Soluble Dietary Fiber on Colonic Transit Time and Clinical Symptoms in Adults With Slow-transit Constipation
Nanjing PLA General Hospital0 个研究点目标入组 80 人开始时间: 2009年5月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 主要终点
- efficacy: intestinal transit time
研究概览
简要总结
The purpose of this study is to investigate the effect of pectin, a kind of soluble dietary fiber, on colonic transit time, clinical symptoms and the gut microbiota in adults with slow-transit constipation.
详细描述
Patients were randomized to receive either pectin or placebo. Treatment consisted of 4 weeks supplementation with pectin (fiber group) or placebo. We evaluated the colonic transit time, constipation symptoms and fecal bacterial population in two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 78 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients(age≧18y)
- •Admitted for slow-transit constipation were considered eligible
排除标准
- •Mental disorders
- •Inflammatory bowel disease
研究组 & 干预措施
soluble dietary fiber
Experimental
pectin, a kind of soluble dietary fiber
干预措施: Pectin (Drug)
结局指标
主要结局
efficacy: intestinal transit time
时间窗: four weeks after inclusion
colonic transit time
次要结局
- efficacy: gut microbiota(four weeks after inclusion)
- efficacy: clinical symptoms(four weeks after inclusion)
研究者
Gao Tao
Nanjing PLA General Hospital
Nanjing PLA General Hospital
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