Effect of Fixed Prosthodontic Rehabilitation on Nutritional and Metabolic Parameters in Patients With Ischemic Heart Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Change in Hemoglobin A1c (HbA1c)
研究概览
简要总结
This study evaluated the effect of fixed prosthodontic rehabilitation on metabolic parameters and masticatory efficiency in patients with ischemic heart disease. Clinical and laboratory outcomes was assessed before and after treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 45 to 70 years with diagnosed stable ischemic heart disease.
- •Patients presenting with partial edentulism and compromised masticatory function due to missing teeth.
- •Patients indicated for fixed prosthodontic rehabilitation.
- •Patients with complete clinical records and laboratory data available at baseline and 6 months after treatment.
- •Patients who provided informed consent for treatment and use of their clinical data.
排除标准
- •uncontrolled systemic diseases affecting metabolic status (e.g., uncontrolled diabetes mellitus).
- •acute cardiovascular events or unstable ischemic heart disease.
- •Patients with conditions affecting oral function other than tooth loss (e.g., neuromuscular disorders).
- •Patients who received removable prostheses instead of fixed prosthodontic rehabilitation.
- •Patients with incomplete clinical records or missing baseline or 6-month laboratory data.
结局指标
主要结局
Change in Hemoglobin A1c (HbA1c)
时间窗: Baseline and 6 months after fixed prosthodontic rehabilitation
Hemoglobin A1c (HbA1c) (%) measured using standard laboratory methods. The mean change in HbA1c from baseline to 6 months after fixed prosthodontic rehabilitation will be assessed.
Change in High-Density Lipoprotein Cholesterol (HDL-C)
时间窗: Baseline and 6 months after fixed prosthodontic rehabilitation
High-density lipoprotein cholesterol (HDL-C) concentration (mg/dL) measured using standard laboratory blood analysis. The mean change in HDL-C from baseline to 6 months after fixed prosthodontic rehabilitation will be assessed.
Change in Low-Density Lipoprotein Cholesterol (LDL-C)
时间窗: Baseline and 6 months after fixed prosthodontic rehabilitation
Low-density lipoprotein cholesterol (LDL-C) concentration (mg/dL) measured using standard laboratory blood analysis. The mean change in LDL-C from baseline to 6 months after fixed prosthodontic rehabilitation will be assessed.
次要结局
未报告次要终点
研究者
Dr. Moaz Mohamed
lecturer of fixed prosthodontics
Tanta University