A Protocol to Wean From Noninvasive Mechanical Ventilation
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- The duration of noninvasive mechanical ventilation
研究概览
简要总结
The investigators use a protocol to wean from noninvasive mechanical ventilation.
详细描述
Design: Prospective, randomized, controlled trial, with 2 groups: study (protocol weaning group) and control (clinicians' order weaning group). Setting: Respiratory Intensive Care Unit (RICU). Subjects: Patients >18 yr, noninvasive mechanical ventilation >24 hours. Interventions and measurements: Study group (weaning as the protocol) and control group (weaning as the clinicians' order); recording of clinical variables at admission and during RICU stay, and end-point variables (noninvasive mechanical ventilation day, RICU and hospital stay, RICU mortality. Expected results: the protocol group's noninvasive mechanical ventilation days is less than clinicians' order group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •noninvasive mechanical ventilation > 24 hours.
- •age >18 years
排除标准
- •severe cerebraI，heart，hepatic and renal faiIure.
- •facial or cranial trauma or surgery.
- •facial abnormalities.
- •recent gastric or esophageal surgery.
- •active upper gastrointestinal bleeding.
- •large amount of sputum with weak cough ability
- •lack of co-operation.
结局指标
主要结局
The duration of noninvasive mechanical ventilation
时间窗: from admission to ICU to discharge from it (average of 4 weeks)
The duration of noninvasive mechanical ventilation was measured from the patients admitted to ICU to discharged from it,an expected average of 4 weeks.
次要结局
- The successful weaning rate(from admission to ICU to discharge from it (average of 4 weeks))
- The length of ICU days(from admission to ICU to discharge from it (average of 4 weeks))
- The intubation rate during the study(from admission to ICU to discharge from it (average of 4 weeks))
- The mortality during the study(from admission to ICU to discharge from it (average of 4 weeks))
研究者
Duan jun
The first affiliated hospital of chong qing medical univercity
Chongqing Medical University