NCT02158156Unknown不适用
Effect of Aerobic Training in Patients With Oculopharyngeal Muscular Dystrophy
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 8
- 试验地点
- 2
- 主要终点
- Efficacy based on VO2max
研究概览
简要总结
The investigators want to investigate if patients with Oculopharyngeal Muscular Dystrophy can improve fitness by home-training on a cycle ergometer 30 minute, 3 times a week for 10 weeks.
Participants will be evaluated on maximal oxygen consumption and maximal workload measured by an incremental test at baseline and at the end of the exercise period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Danish patients with Oculopharyngeal muscular dystrophy
排除标准
- •Patients who are too week to train on an cycle-ergometer for 10 weeks
- •Patients with other health issues wich confound the interpretation of the efficacy.
结局指标
主要结局
Efficacy based on VO2max
时间窗: 10 weeks
Difference in VO2max measured before and after intervention
次要结局
- Intensity in maximal load (Watt)(10 weeks)
- Dynamometry(10 weeks)
- SF-36 Questionaire(10 weeks)
- Level of plasma creatine kinase(10 weeks)
- Level of plasma myoglobin(10 weeks)
- A five-time-repetition-sit-to-stand-test(10 weeks)
- A 14-step-stair-test(10 weeks)
- 6 minute walk test(10 weeks)
研究者
Karen Brorup Heje Pedersen
Bsc Medicine
Rigshospitalet, Denmark
研究点 (2)
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