NCT01280825招募中不适用
The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,200
- 试验地点
- 1
- 主要终点
- Feasibility of incorporating pharmacogenomic testing into routine medical care
研究概览
简要总结
The purpose of this study is to collect DNA samples from patients undergoing routine care at the University of Chicago. These samples will be tested for differences in genes that may suggest greater risk of side effects or chance of increased benefit from certain medications. The results will be made available to the patient's treating physician and the researchers will track whether or not this information is used in routine health care.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Receiving ongoing, out-patient care at the University of Chicago Medical Center under the routine care of a physician participating in this trial
- •Life expectancy of at least 3 years
- •Must be 18 years or older
- •Must be taking at least 1 (but not more than 6) prescription medications at the time of enrollment OR be 65 years or older OR be reasonably expected to require the use of a prescription medication within the next 5 years
- •Patients with certain diseases, or likely to receive or be receiving certain drugs, will be targeted particularly for enrollment in order to enrich the study for patients likely to have pharmacogenetically relevant interactions, including, but not limited to:
- •Patients requiring specialized cardiology care
- •Patients with inflammatory bowel diseases
- •Patients with systemic autoimmune or inflammatory diseases
- •Patients requiring long-term oral anticoagulation
- •Patients with hepatitis C
- •Patients with non-metastatic cancer
排除标准
- •Patients with acute or chronic disease which could be reasonably expected to result in the patient's death within the next 3 years.
- •Patients who have undergone, or are being actively considered for, liver or kidney transplantation.
- •Inability to understand and give informed consent to participate.
研究组 & 干预措施
Adult Patients
Adults receiving health care at the University of Chicago Medical Center.
结局指标
主要结局
Feasibility of incorporating pharmacogenomic testing into routine medical care
时间窗: 5 years
次要结局
- Find out whether availability of pharmacogenomic information impacts drug decision making in the health care setting(5 years)
研究者
研究点 (1)
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