A comparative evaluation of clinical and radiographic periapical healing after continuous and sequential chelation irrigation protocols in teeth with periapical pathology – A Randomized Clinical Study
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- The result of the study will help us to determine the efficacy of sequential & continuous chelation irrigation protocols in a tooth with periapical pathology. Moreover, it will help practitioner to get better idea of both irrigation regimes.
研究概览
简要总结
Theoutcome of endodontic treatment depends critically on the removal of microbes,necrotic tissues, and accumulated hard tissue debris which is mechanical instrumentation and strongantibacterial irrigation followed by well-sealed obturation of the root canalsystem can significantly reduce the bacterial load and create an environmentconducive to healing.
Sodium Hypochlorite shows excellent antimicrobialand tissue dissolving properties but, to remove smear layer chelating agentsare required. Combination of both (Continuous Chelation Irrigation) is bestseen with mixture of 2.5% sodium hypochlorite and 9% HEDP solution.
Asminimal literature is available on the clinical efficacy of continuous chelationirrigation protocols in teeth with periapical pathology. The present study compares the use of 2.5%sodium hypochlorite & 17%EDTA (sequential chelation irrigation) withsolution of 2.5% sodium hypochlorite and 9% etidronate (HEDP) as rootcanal irrigant in teethwith periapical pathology.
Therefore,the aim of the study is to compare the clinical and radiographical evaluationof periapical healing of continuous and sequential chelation irrigationprotocols in teeth with periapical pathology.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Healthy patients (Category: American Society of Anaesthesiologists class 1) (ASA House of Delegates 2014) aged between 18 – 60 years of age will be included.
- •2.Maxillary or mandibular teeth diagnosed with periapical pathology not more than 3mm (Periapical Index less than 4 given by Orstavik et al20) in dimension will be included.
- •3.Only those patients ready to sign the consent form will be included in the study.
排除标准
- •1.Teeth with open apex, root resorption and calcified pulp chamber and canals will be excluded from the study.
- •2.Teeth with curvature more than 20 degree will be excluded from the study 3.Teeth which had received previous endodontic treatment will be excluded from the study.
- •4.Cases showing periodontal pockets deeper than 4mm will be excluded from the study.
- •5.Teeth with Flare ups during root canal treatment will be excluded from the study.
- •6.Any other iatrogenically affected root canal treatments will be excluded from the study.
- •7.Medically compromised patients will be excluded from the study.
结局指标
主要结局
The result of the study will help us to determine the efficacy of sequential & continuous chelation irrigation protocols in a tooth with periapical pathology. Moreover, it will help practitioner to get better idea of both irrigation regimes.
时间窗: The result of the study will help us to determine the efficacy of sequential & continuous chelation irrigation protocols in a tooth with periapical pathology. Moreover, it will help practitioner to get better idea of both irrigation regimes. This will be assessed at baseline, 3 months and 6 months.
次要结局
未报告次要终点