Unilateral Dual Transversus Abdominis Plane Block in Pediatric Renal Transplant: A Randomized Control Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- total dose of rescue analgesia
研究概览
简要总结
Alleviating pain in children undergoing renal transplant is extremely challenging. Large incisions as those of renal transplant (Gibson's incision) require special techniques of pain control that don't affect hemodynamics or renal function. Since the transplant incision doesn't cross midline; a dual-TAP block is thought to be effective in providing pain control in such procedure as it will anesthetize the dermatomes T6-T12, the muscles of the anterior abdominal wall together with the underlying parietal peritoneum.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 3 Years 至 16 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •3-16 years
- •end stage renal disease
- •no known allergy to bupivacaine
- •both sexes
排除标准
- •known allergy to bupivacaine
研究组 & 干预措施
dual TAB group
22 patients will receive unilateral dual transversus abdominis plane (TAB) block USING bupivacaine 0.25% at a dose of 2 mg/kg
干预措施: bupivacaine (Drug)
dual TAB group
22 patients will receive unilateral dual transversus abdominis plane (TAB) block USING bupivacaine 0.25% at a dose of 2 mg/kg
干预措施: Pethidine (Drug)
dual TAB group
22 patients will receive unilateral dual transversus abdominis plane (TAB) block USING bupivacaine 0.25% at a dose of 2 mg/kg
干预措施: perfalgan (Drug)
dual TAB group
22 patients will receive unilateral dual transversus abdominis plane (TAB) block USING bupivacaine 0.25% at a dose of 2 mg/kg
干预措施: fentanyl (Drug)
control group
22 patients who will not receive dual TAB block
干预措施: Pethidine (Drug)
control group
22 patients who will not receive dual TAB block
干预措施: perfalgan (Drug)
control group
22 patients who will not receive dual TAB block
干预措施: fentanyl (Drug)
结局指标
主要结局
total dose of rescue analgesia
时间窗: from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours
pethidine given as rescue analgesia postoperative.
次要结局
- Intraoperative blood pressure(from the induction of anesthesia till end of surgery at half an hour intervals average duration is 4 hours)
- pain scoring system (objective behavioural pain score)(from the time of transfer to the nephrology ICU, every hour for the first 24 hours postoperative)
- postoperative heart rate(from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours)
- intraoperative heart rate(from the induction of anesthesia till end of surgery at half an hour intervals average duration is 4 hours)
- postoperative blood pressure(from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours)
研究者
Sherif Mohamed Abd el moneim Soaida, MD
Assistant Professor
Cairo University