Caudal Extradural Catheterization in Pediatric Renal Transplant: Effect on Perioperative Hemodynamics and Pain Scoring.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Intraoperative blood pressure
研究概览
简要总结
pain control in pediatric renal transplant is a major concern. the main goal during anesthesia of renal transplant in pediatrics is to maintain hemodynamics in a range close to that of the adult donor. epidural analgesia is thought to be very effective in pain control. this study emphasises the ease of application of epidural catheter via the caudal route to the lower thoracic level; avoiding possible complications that may arise from lumbar or thoracic routes, and its effects on hemodynamics when using analgesic doses of local anesthetics and narcotics.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- None
入排标准
- 年龄范围
- 3 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •3-12 years
- •end stage renal disease
- •no known allergy to bupivacaine
- •both sexes
排除标准
- •known allergy to bupivacaine
- •inflammation at caudal area
- •spinal cord deformity
研究组 & 干预措施
control group
30 patients didn't receive caudal epidural analgesia
干预措施: Fentanyl (Drug)
caudal epidural catheterization group
30 patients received continuous intra and post-operative caudal epidural infusion of bupivacaine 0.125% with fentanyl (2 microgram/ml) over 24 hours
干预措施: B-Braun, Perifix® ONE Paed, Germany (Device)
caudal epidural catheterization group
30 patients received continuous intra and post-operative caudal epidural infusion of bupivacaine 0.125% with fentanyl (2 microgram/ml) over 24 hours
干预措施: Pethidine (Drug)
caudal epidural catheterization group
30 patients received continuous intra and post-operative caudal epidural infusion of bupivacaine 0.125% with fentanyl (2 microgram/ml) over 24 hours
干预措施: Propofol (Drug)
caudal epidural catheterization group
30 patients received continuous intra and post-operative caudal epidural infusion of bupivacaine 0.125% with fentanyl (2 microgram/ml) over 24 hours
干预措施: Bupivacaine (Drug)
caudal epidural catheterization group
30 patients received continuous intra and post-operative caudal epidural infusion of bupivacaine 0.125% with fentanyl (2 microgram/ml) over 24 hours
干预措施: Fentanyl (Drug)
control group
30 patients didn't receive caudal epidural analgesia
干预措施: Pethidine (Drug)
control group
30 patients didn't receive caudal epidural analgesia
干预措施: Propofol (Drug)
结局指标
主要结局
Intraoperative blood pressure
时间窗: from the induction of anesthesia till end of surgery at half an hour intervals
measure systolic and diastolic blood pressure
次要结局
- postoperative central venous pressure(from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours)
- postoperative blood pressure(from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours)
- postoperative heart rate(from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours)
- intraoperative central venous pressure(fromom the induction of anesthesia till end of surgery at half an hour intervals)
- intraoperative heart rate(from the induction of anesthesia till end of surgery at half an hour intervals)
研究者
Sherif Mohamed Abd el moneim Soaida, MD
Lecturer
Cairo University