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Clinical Trials/NCT03368833
NCT03368833
Terminated
Not Applicable

Caudal Blockade and Electrocardiographic Changes

Senthil G. Krishna1 site in 1 country5 target enrollmentDecember 15, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Regional Anesthesia Morbidity
Sponsor
Senthil G. Krishna
Enrollment
5
Locations
1
Primary Endpoint
Change in T wave amplitude
Status
Terminated
Last Updated
3 years ago

Overview

Brief Summary

Caudal epidural blockade is frequently used as an adjunct to general anesthesia in children for perioperative analgesia. Intravascular injection of local anesthetic is a known complication that can adversely affect the neurological and cardiovascular systems. This study will look at the delayed effects of a caudal epidural block on the electrical activity of the patient's myocardium by trying to characterize the incidence of ECG changes within 60 minutes after the caudal dose is given.

Registry
clinicaltrials.gov
Start Date
December 15, 2017
End Date
September 6, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Senthil G. Krishna
Responsible Party
Sponsor Investigator
Principal Investigator

Senthil G. Krishna

Attending Anesthesiologist

Nationwide Children's Hospital

Eligibility Criteria

Inclusion Criteria

  • ASA grade 1 or 2
  • Receiving general anesthesia with a caudal block

Exclusion Criteria

  • Preexisting cardiac comorbidities

Outcomes

Primary Outcomes

Change in T wave amplitude

Time Frame: Baseline to 60 mins. post caudal

Change in T wave amplitude on the ECG tracings

Change in T wave width

Time Frame: Baseline to 60 mins. post caudal

Change in T wave width on the ECG tracings

Study Sites (1)

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