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Clinical Trials/NCT04292782
NCT04292782
Completed
Not Applicable

Caudal Epidural Block Compared to Anterior Quadratus Lumborum Block for Pediatric Hip Surgery

University Tunis El Manar1 site in 1 country40 target enrollmentMarch 31, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hip Dislocation, Congenital
Sponsor
University Tunis El Manar
Enrollment
40
Locations
1
Primary Endpoint
analgesics consumption
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Caudal blockade (CB) is one of the most frequently performed regional anaesthetic techniques in children. It's an efficient way to offer perioperative analgesia for painful sub-umbilical interventions but with high incidence of motor block and urinary retention. In one study, psoas compartment block was associated with less morphine comsumption and prolonged duration of analgesia compared to single-shot caudal Block in small children undergoing open hip reduction/osteotomies. Ultasound guided anterior Quadratus lumborum block (AQLB) provides unilateral analgesia to the nerves between the psoas muscle (PM) and the quadratus lumborum muscle (QLM). The first pediatric study evaluating Quadratus lumborum block is encouraging .

The first pediatric study evaluating Quadratus lumborum block is encouraging. To the best of the investigator's knowledge, there are no previously published data comparing the AQLB with other regional techniques in infants undergoing hip surgery.

Detailed Description

The aim of this prospective randomized study was to compare the analgesic effects between AQLB and CB in children undergoing unilateral open hip reduction/osteotomies for hip dislocation. Patients were randomly assigned, into 1 of 2 groups, namely, group CB (n = 20) and group AQLB (n = 20). Preoperatively all children were premedicated by using oral midazolam (0 .5mg/kg). anesthesia was induced with 3 to 4% sevoflurane and 50% with 60% nitrous oxide in oxygen.Then fentanyl 3 μg/kg and Propofol 1 - 2mg/Kg were administered for anesthesia induction. Airway was secured with endotracheal tube placed in the mouth facilited by 0.15 mg/kg cistracurium. Anesthesia maintenance was performed with sevoflurane 2% in 50% nitrous oxide. AQLB and CB were done with 1 ml/kg, 0.25% Ropivacaine (maximum dose limited to 20 ml) Postoperative follow-up: All patients received 15 mg/kg paracetamol before extubation. Tramadol 2 mg/kg intravenous was planned as rescue analgesia when CHEOPS score was more than 3. Supplemental IV tramado, 1 mg/kg could be added if necessary every 6 hours.

Registry
clinicaltrials.gov
Start Date
March 31, 2020
End Date
December 31, 2021
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University Tunis El Manar
Responsible Party
Principal Investigator
Principal Investigator

Olfa kaabachi, MD

Professor

University Tunis El Manar

Eligibility Criteria

Inclusion Criteria

  • Patients aged 2 to 7 years old
  • Weight ≤ 20 Kg
  • American Society of Anesthesiologists (ASA) physical status I or II
  • Planned to undergo unilateral open hip reduction/osteotomies

Exclusion Criteria

  • Cerebral palsy with severe intellectual disability
  • Coagulation disorders
  • Local or general infection
  • Allergy to amide local anesthetics.
  • Progressive neurological disorders
  • Parenteral refusal
  • Spinal dysraphism
  • Cutaneous anomalies (angioma, hair truft, naevus or a dimple)near to the puncture

Outcomes

Primary Outcomes

analgesics consumption

Time Frame: day one

total tramadol consumption

Secondary Outcomes

  • analgesic rescue(Day one)
  • postoperative pain score(day one)

Study Sites (1)

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