Preemptive Analgesia in Children Using Caudal Epidural Ropivacaine: A Prospective, Randomized, Double-blinded, Controlled Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Inguinal Hernia
- Sponsor
- Loma Linda University
- Enrollment
- 90
- Locations
- 2
- Primary Endpoint
- Usage of pain medications
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Caudal epidural analgesia (caudal block)is used in standard pediatric anesthesia practice. It has been shown to be effective in managing postoperative pain in children undergoing abdominal and infraumbilical surgery (Tobias et al 1994). Furthermore, studies have shown that children receiving caudal blocks have secondary benefits such as lower narcotic and anesthetic requirements, more rapid awakening from general anesthesia, decreased time to discharge home, and fewer pain-related behaviors postoperatively (Conroy et al 1993, Tobias et al 1995, Tobias 1996).
This proposed study involves the use of a caudal block in children undergoing elective inguinal herniorrhaphy or orchiopexy to evaluate the role of preemptive analgesia in pediatric pain management. We hypothesize that by inhibiting peripheral pain receptors with a caudal block before the onset of a painful stimulus, we can decrease central nervous system sensitization and reduce postoperative analgesic requirements
Investigators
Shannon Mulder, MD
M.D.
Loma Linda University
Eligibility Criteria
Inclusion Criteria
- •Age 2 months to 2 years
- •Weight 25kg or less
- •ASA class 1, 2, 3
- •Elective inguinal herniorrhaphy or orchiopexy
Exclusion Criteria
- •Contraindications to caudal epidural analgesia
- •parent's refusal
- •skeletal or spinal cord anomaly
- •coagulopathy
- •infection at the insertion site
- •ongoing bacteremia
- •allergy to ropivacaine
Outcomes
Primary Outcomes
Usage of pain medications
Time Frame: over 24 hours
Secondary Outcomes
- Pain scores(At various intervals for first 24 hours)