Preemptive Analgesia in Children Using Caudal Epidural Ropivacaine: A Prospective, Randomized, Double-blinded, Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 2
- 主要终点
- Usage of pain medications
研究概览
简要总结
Caudal epidural analgesia (caudal block)is used in standard pediatric anesthesia practice. It has been shown to be effective in managing postoperative pain in children undergoing abdominal and infraumbilical surgery (Tobias et al 1994). Furthermore, studies have shown that children receiving caudal blocks have secondary benefits such as lower narcotic and anesthetic requirements, more rapid awakening from general anesthesia, decreased time to discharge home, and fewer pain-related behaviors postoperatively (Conroy et al 1993, Tobias et al 1995, Tobias 1996).
This proposed study involves the use of a caudal block in children undergoing elective inguinal herniorrhaphy or orchiopexy to evaluate the role of preemptive analgesia in pediatric pain management. We hypothesize that by inhibiting peripheral pain receptors with a caudal block before the onset of a painful stimulus, we can decrease central nervous system sensitization and reduce postoperative analgesic requirements
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 2 Months 至 2 Years(Child)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 2 months to 2 years
- •Weight 25kg or less
- •ASA class 1, 2, 3
- •Elective inguinal herniorrhaphy or orchiopexy
排除标准
- •Contraindications to caudal epidural analgesia
- •parent's refusal
- •skeletal or spinal cord anomaly
- •coagulopathy
- •infection at the insertion site
- •ongoing bacteremia
- •allergy to ropivacaine
结局指标
主要结局
Usage of pain medications
时间窗: over 24 hours
次要结局
- Pain scores(At various intervals for first 24 hours)
研究者
Shannon Mulder, MD
M.D.
Loma Linda University
