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临床试验/NCT01494272
NCT01494272已完成不适用

Preemptive Analgesia in Children Using Caudal Epidural Ropivacaine: A Prospective, Randomized, Double-blinded, Controlled Study

Loma Linda University2 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2012年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
90
试验地点
2
主要终点
Usage of pain medications

研究概览

简要总结

Caudal epidural analgesia (caudal block)is used in standard pediatric anesthesia practice. It has been shown to be effective in managing postoperative pain in children undergoing abdominal and infraumbilical surgery (Tobias et al 1994). Furthermore, studies have shown that children receiving caudal blocks have secondary benefits such as lower narcotic and anesthetic requirements, more rapid awakening from general anesthesia, decreased time to discharge home, and fewer pain-related behaviors postoperatively (Conroy et al 1993, Tobias et al 1995, Tobias 1996).

This proposed study involves the use of a caudal block in children undergoing elective inguinal herniorrhaphy or orchiopexy to evaluate the role of preemptive analgesia in pediatric pain management. We hypothesize that by inhibiting peripheral pain receptors with a caudal block before the onset of a painful stimulus, we can decrease central nervous system sensitization and reduce postoperative analgesic requirements

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
2 Months 至 2 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Age 2 months to 2 years
  • Weight 25kg or less
  • ASA class 1, 2, 3
  • Elective inguinal herniorrhaphy or orchiopexy

排除标准

  • Contraindications to caudal epidural analgesia
  • parent's refusal
  • skeletal or spinal cord anomaly
  • coagulopathy
  • infection at the insertion site
  • ongoing bacteremia
  • allergy to ropivacaine

结局指标

主要结局

Usage of pain medications

时间窗: over 24 hours

次要结局

  • Pain scores(At various intervals for first 24 hours)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Shannon Mulder, MD

M.D.

Loma Linda University

研究点 (2)

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