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Clinical Trials/NCT01494272
NCT01494272
Completed
Not Applicable

Preemptive Analgesia in Children Using Caudal Epidural Ropivacaine: A Prospective, Randomized, Double-blinded, Controlled Study

Loma Linda University2 sites in 1 country90 target enrollmentJune 2012

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Inguinal Hernia
Sponsor
Loma Linda University
Enrollment
90
Locations
2
Primary Endpoint
Usage of pain medications
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

Caudal epidural analgesia (caudal block)is used in standard pediatric anesthesia practice. It has been shown to be effective in managing postoperative pain in children undergoing abdominal and infraumbilical surgery (Tobias et al 1994). Furthermore, studies have shown that children receiving caudal blocks have secondary benefits such as lower narcotic and anesthetic requirements, more rapid awakening from general anesthesia, decreased time to discharge home, and fewer pain-related behaviors postoperatively (Conroy et al 1993, Tobias et al 1995, Tobias 1996).

This proposed study involves the use of a caudal block in children undergoing elective inguinal herniorrhaphy or orchiopexy to evaluate the role of preemptive analgesia in pediatric pain management. We hypothesize that by inhibiting peripheral pain receptors with a caudal block before the onset of a painful stimulus, we can decrease central nervous system sensitization and reduce postoperative analgesic requirements

Registry
clinicaltrials.gov
Start Date
June 2012
End Date
May 2015
Last Updated
10 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Shannon Mulder, MD

M.D.

Loma Linda University

Eligibility Criteria

Inclusion Criteria

  • Age 2 months to 2 years
  • Weight 25kg or less
  • ASA class 1, 2, 3
  • Elective inguinal herniorrhaphy or orchiopexy

Exclusion Criteria

  • Contraindications to caudal epidural analgesia
  • parent's refusal
  • skeletal or spinal cord anomaly
  • coagulopathy
  • infection at the insertion site
  • ongoing bacteremia
  • allergy to ropivacaine

Outcomes

Primary Outcomes

Usage of pain medications

Time Frame: over 24 hours

Secondary Outcomes

  • Pain scores(At various intervals for first 24 hours)

Study Sites (2)

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