NCT04584047已完成不适用
Evaluation of Cell-based Non-invasive Prenatal Testing as an Alternative to Chorionic Villus Sampling as a Tool to Confirm the Pregnancy With an Unaffected Fetus Following Preimplantation Genetic Testing
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 2
- 主要终点
- Agreement between cbNIPT and CVS (The gold standard)
研究概览
简要总结
The study aims to investigate whether cell-based non-invasive prenatal testing (cbNIPT) can be used as an alternative to invasive chorionic villus sampling (CVS) in patients who achieve pregnancy following preimplantation genetic testing for monogenic disorders (PGT-M).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Achieved pregnancy following preimplantation genetic testing
排除标准
- 未提供
结局指标
主要结局
Agreement between cbNIPT and CVS (The gold standard)
时间窗: Immidiately after the results from cbNIPT and CVS has been obtained
How do the cbNIPT results compare to the results of the genetic test following CVS
次要结局
- Effectiveness of fetal cell isolation(Immidiately after genetic testing of the isolated fetal cells)
- Effectiveness of testing the genetic variant of interest(Immidiately after genetic testing of the isolated fetal cells)
研究者
Christian Liebst Frisk Toft
Molecular Biologist, Ph.D. fellow
Aalborg University Hospital
研究点 (2)
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