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临床试验/NCT01952977
NCT01952977已完成不适用

Effect of Medium Chain Triglyceride Consumption on Appetite

St. Luke's-Roosevelt Hospital Center1 个研究点 分布在 1 个国家目标入组 17 人开始时间: 2010年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
17
试验地点
1
主要终点
Food intake

研究概览

简要总结

The purpose of this study is to test the effects of medium chain triglyceride consumption, relative to long chain triglycerides, on hormones involved in appetite regulation and food intake in overweight men. We expect medium chain triglycerides to reduce appetite and food intake and to do so by increasing levels of hormones known to be involved in satiety and reduce levels of those involved in appetite.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
盲法
Single (Participant)

入排标准

年龄范围
19 Years 至 50 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Weight stable (<10 lb over previous 3 months)
  • Overweight (body mass index 25-29.9)

排除标准

  • Excessive caffeine users
  • Severe health conditions
  • Allergy to food products/ingredients in the study
  • Taking medications known to affect energy expenditure or gastrointestinal function

结局指标

主要结局

Food intake

时间窗: up to 3 hours

Intake at an ad libitum meal 3 h after test oil consumption (Study 1) or 1 h after a pre-load containing the test oil (Study 2)

次要结局

  • Peptide YY(3 hours)
  • Glucagon-like peptide 1(3 hours)
  • Insulin(3 hours)
  • Triglycerides(3 hours)
  • Leptin(3 hours)
  • Ghrelin(3 hours)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Marie-Pierre St-Onge

Research Associate

St. Luke's-Roosevelt Hospital Center

研究点 (1)

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