OSV-IRM - Volunteer MRI Sequence Optimization
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 600
- 试验地点
- 2
- 主要终点
- Quality of MRI signal
研究概览
简要总结
Optimization of magnetic resonance imaging (MRI) protocols on healthy volunteers and voluntary patients.
In MRI, a large number of technical parameters (sequence, parameters in sequence, antenna, reconstruction method, etc.) can be changed to optimize the diagnostic quality of the exam. Some optimizations can be performed on participants healthy volunteers, others need to be carried out on images pathological and acquired in voluntary patients.
详细描述
An inclusion visit is planned to verify the criteria for selection, then an imaging visit to perform the MRI examination.
The imaging visit can take place at the end of the inclusion visit and until the following 15 days. For healthy volunteers, the visits are organized according to their availability. For patients, on the other hand, participation in the research will depend on the programming of the MRI within the framework care.
This is a single-center prospective study carried out at two sites in the Rennes University Hospital.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 6 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Criteria common to all participants:
- •Minor or major subject
- •Affiliated, himself or through his parents if he is a minor, to a a social security scheme
- •Having given their free, informed and written consent, and/or which the free, informed and written consent of the holder(s) parental authority has been obtained for minors
- •Specific criteria for healthy volunteers:
- •o No medical or surgical history related to the anatomical area(s) scanned
- •Specific criteria for voluntary patients:
- •o Indication for an MRI exam as part of its management
排除标准
- •- Contraindication to an MRI (pacemaker or pacemaker, neurostimulator, intra-orbital metal body, vascular clip ferromagnetic)
- •Pregnancy
- •Legal protection measure for adults in progress (safeguard of justice, guardianship, curatorship) or subject deprived of liberty
结局指标
主要结局
Quality of MRI signal
时间窗: 15 days
The quality of the images, maps or signals collected will be compared to standard acquisitions. This evaluation will be done by statistical comparison of visual qualitative criteria by expert radiologists or on quantitative criteria drawn from analyzes computing data obtained by processing experts images (signal-to-noise ratio, contrast-to-noise ratio, blur level, mutual information, co-location of regions highlighted by different techniques, etc.).
次要结局
未报告次要终点