Effect of preoperative administration of intravenous parecoxib on postoperative morphine consumption after video-assisted thoracoscopic surgery

Faculty of Medicine, Khon Kaen University0 个研究点目标入组 46 人开始时间: 2017年12月13日最近更新: 2024年8月19日

研究概览

简要总结

Perioperative administration of two dosages of parecoxib 40 mg intravenously every 12 hours could significantly reduce postoperative cumulative morphine consumption at 24 hours, and NRS pain score at rest and on coughing in 24 hours in patients undergone VATS.

研究设计

研究类型: Interventional

入排标准

年龄范围: 18 Years 至 65 Years（—）
性别: All

入选标准

•1. patients who undergoing elective video-assisted thoracoscopic surgery
•2. Age between 18-65 years old
•3. ASA status I-III

排除标准

•-History of chronic analgesic use (nonsteroidal anti-inflammatory drugs; NSAIDS, opioids, or paracetamol)
•-Presence of a chronic pain disorder (i.e. back pain, cancer, arthritis)
•-Inability to use the PCA device
•-Allergy to the study drugs: parecoxib and morphine
•-Neurological disease or major psychiatric disorder
•- Pregnancy

研究者

发起方

Faculty of Medicine, Khon Kaen University

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