跳至主要内容
临床试验/NCT01788488
NCT01788488已完成不适用

Impact of Measuring Serum Procalcitonin Levels on Duration of Antimicrobial Therapy in Critical Care Patients With Suspected Pneumonia

Mayo Clinic1 个研究点 分布在 1 个国家目标入组 134 人开始时间: 2013年2月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
Mayo Clinic
入组人数
134
试验地点
1
主要终点
Length of antibiotic therapy

研究概览

简要总结

The goal of the study is to determine the impact of procalcitonin (PCT)-guided therapy on duration of antibiotic therapy in critical care unit (CCU) patients with suspected pneumonia at Mayo Clinic Health System Eau Claire.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •18 years old
  • •admitted to critical care unit
  • •placed on pneumonia protocol

排除标准

  • •patients who received outpatient antibiotic therapy within previous 21 days

研究组 & 干预措施

Standard Therapy

No Intervention

Procalcitonin-guided therapy

Experimental

Procalcitonin levels will be measured to determine when it is appropriate to discontinue antibiotic therapy.

干预措施: Use of procalcitonin as biomarker to guide therapy (Other)

结局指标

主要结局

Length of antibiotic therapy

时间窗: Indefinite

Participants will be followed for the entire time they are on antibiotics to treat pneumonia, an expected average of 30 total antibiotic days.

次要结局

  • Length of stay in critical care unit(Indefinite)
  • Cost(Once)
  • Length of stay in the hospital(Indefinite)

研究者

发起方
Mayo Clinic
申办方类型
Other
责任方
Principal Investigator
主要研究者

Kent H. Gierhart

PI

Mayo Clinic

研究点 (1)

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