NCT00642447已完成2 期
Helium:Oxygen Versus Air:Oxygen Nonivasive Positive Pressure Ventilation in Patients Exposed to Sulfur Mustard
Baqiyatallah Medical Sciences University2 个研究点 分布在 1 个国家目标入组 23 人开始时间: 2007年4月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 23
- 试验地点
- 2
研究概览
简要总结
to assess the effect of Heliox with Noninvasive positive pressure ventilation to decrease dyspnea and improve physiologic and respiratory measures in patients with a previous exposure to Sulfur Mustard gas.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 38 Years 至 59 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •exposure to sulfur mustard
- •worsening dyspnea during the last 10 days
- •respiratory rate of >25/min
- •arterial pH<7.35
- •PaCO2 of >50 mmHg
- •PaO2 of <50 mmHg
排除标准
- •recent pneumothorax (<1 month)
- •severe respiratory failure or hemodynamic instability with forthcoming intubation
- •FIO2 of <0.4
- •impaired consciousness or absence of patient cooperation
- •facial lesions precluding NIPPV
研究者
研究点 (2)
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