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临床试验/NCT04344340
NCT04344340已完成不适用

The Association Between MIH and HSPM

Cairo University1 个研究点 分布在 1 个国家目标入组 190 人开始时间: 2021年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
190
试验地点
1
主要终点
The prevalence of hypomineralized second primary molars.

研究概览

简要总结

Aim of the Study Evaluate association between HSPM and MIH in Egyptian children. Record the prevalence of HSPM and MIH in Egyptian children

详细描述

Statement of the Problem:

Molar Incisor Hypomineralization (MIH) is defined as developmental qualitative defect of systemic origin, which affects one to four of first permanent molars and frequently associated with permanent incisors . The prevalence of MIH worldwide was reported from 2.4% to40.2% and clinical measures of MIH based on scientific criteria was established based on the European Academy of Pediatric Dentistry criteria to allow comparison between the findings of different studies .

The most commonly reported clinical problems for patients with MIH are hypersensitivity of teeth to various thermal and mechanical stimuli result in improper tooth brushing, plaque accumulation and rapid caries progression. Severely affected enamel shows post eruptive breakdown and such teeth require extensive treatment, ranging from prevention to restorations and extractions. MIH patients also have increased risk of developing dental fear and anxiety as well as behavior management problems added to the difficulty to achieve effective local anaesthesia which are related to chronic pulp inflammation from dentin exposure due to excessive enamel breakdown.

Rational As developmental of Second Primary Molar start at the same time as the development of the first permanent molars and incisor but the maturation of permanent teeth occur more slow. So when a systemic disturbance occur it affect second primary molar as well as first permanent molar and incisors.

Few studies test the association between hypomineralized second primary molar (HSPM) and MIH. While no study available on Egyptian children.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Cross Sectional

入排标准

年龄范围
8 Years 至 9 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Children aged from 8 to 9 years.
  • Both genders.
  • No systemic health problems

排除标准

  • Children with extracted primary second molars and permanent incisors and molars.
  • Children with history of dental trauma.
  • Children with orthodontic bands or dental appliances

结局指标

主要结局

The prevalence of hypomineralized second primary molars.

时间窗: 1 year

The percentage of children who has enamel defect on their second primary molars in the study

次要结局

  • the prevalence of Molar Incisor Hypomineralization(1 year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yassmin Mohamed Abdelrahman

principle invistigator

Cairo University

研究点 (1)

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