NCT01310686Unknown不适用
Genotypic Evaluation of Chronic Exudative Macular Degeneration Despite Monthly Anti-Vascular Endothelial Growth Factor (VEGF) Therapy
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Genetic analysis of patients with chronic wet age-related macular degeneration despite continuous anti-VEGF treatment
研究概览
简要总结
To obtain a genotypic analysis of patients with chronic exudative age-related macular degeneration noted to have subretinal or intraretinal edema despite continuous monthly Anti-VEGF therapy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Ability to provide written informed consent for participation in this study
- •Subjects diagnoses of neovascular AMD who are on a monthly anti-VEGF regimen (have had >10 or more ranibizumab and/or bevacizumab injections within the last year) and who still have intra-retinal or subretinal fluid as confirmed by the Investigator
排除标准
- •Subjects with a Pigment Epithelial Detachment Exclusively
- •Subjects with Serous Pigment Epithelial Detachments
- •Subjects with history of the following:
- •idiopathic polypoidal choroidal vasculopathy
- •pathologic degenerative myopia
- •central serous chorioretinopathy
- •familial drusen
- •adult onset foveal pattern dystrophy
结局指标
主要结局
Genetic analysis of patients with chronic wet age-related macular degeneration despite continuous anti-VEGF treatment
时间窗: This is a one time only blood draw.
次要结局
- To evaluate demographic and clinical characteristics in patients treated with anti-VEGF therapy who fail to respond completely.(This is a one time only blood draw and assessment of clinical characteristics.)
研究者
Arthur D. Fu, MD
Principal Investigator
West Coast Retina Medical Group, Inc.
研究点 (1)
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