Effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) as an adjuvant for Severe Depression
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To assess the effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) as an adjuvant in Severe Depression.
研究概览
简要总结
rTMS is an emerging treatment for depression, particularly when administered to the left dorsal prefrontal cortex for an antidepressant effect. Clinical evidence suggests that rTMS is effective when administered during a depressive episode in patients. However, there is a lack of published data on the role of rTMS in depression from India, possibly due to limited availability of the facility in mental health centers. Clinical data from hospital settings can help bridge the gap between RCTs and the actual effects of rTMS in typical practice settings. Therefore, this study is aimed at assessing the effectiveness of rTMS as an adjuvant in treating severe depression in our hospital setting.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Right Handed patients 2.Of Ages 18-60 Years, Of Both Sexes, 3.Who Are Diagnosed With Severe Depression According To ICD 11.
排除标准
- •Medical commodities that need immediate attention
- •Any contraindication to rTMS such as any metallic implants in close contact to coil, cochlear implants
- •Any other psychiatric co morbidity.
结局指标
主要结局
To assess the effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) as an adjuvant in Severe Depression.
时间窗: After 10 rTMS sessions
次要结局
- To assess the number of rTMS sessions required to bring(about a response (less than 50% scores) in the identified patients in HDRS.)
- To assess the improvement of functional capacity of the patients using GAF scale with rTMS.(Before and after 10 rTMS sessions)
研究者
Amrutha Gudimetla
NRI Academy of Sciences